Udani Vrajesh, Desai Neelu, Botre Abhijeet
Department of Pediatric Neurology PD Hinduja National Hospital and Medical Research Center Mumbai India.
Mov Disord Clin Pract. 2015 Sep 1;3(1):80-82. doi: 10.1002/mdc3.12221. eCollection 2016 Jan-Feb.
Childhood anti--methyl-d-aspartate receptor (NMDA-R) antibody encephalitis is a well-recognized autoimmune encephalitis presenting typically with a combination of varied movement disorders, seizures, mutism, behavioral and sleep disturbances, and autonomic changes. Monosymptomatic or incomplete forms of the disorder are rare, but have recently been reported. Here, we describe 2 children with nonparaneoplastic anti-NMDA-R encephalitis with partial presentation in the form of movement disorder and minor behavioral changes.
儿童抗N-甲基-D-天冬氨酸受体(NMDA-R)抗体脑炎是一种公认的自身免疫性脑炎,通常表现为多种运动障碍、癫痫发作、缄默症、行为和睡眠障碍以及自主神经改变的组合。该疾病的单症状或不完全形式较为罕见,但最近有相关报道。在此,我们描述2例非副肿瘤性抗NMDA-R脑炎患儿,其以运动障碍和轻微行为改变的形式呈现部分症状。