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美国中央脊髓综合征的流行病学与治疗

Epidemiology and treatment of central cord syndrome in the United States.

作者信息

Segal Dale N, Grabel Zachary J, Heller John G, Rhee John M, Michael Keith W, Yoon S Tim, Jain Amit

机构信息

Department of Orthopedics, Emory University, Atlanta, GA, USA.

Department of Orthopedics, Johns Hopkins University, MD, USA.

出版信息

J Spine Surg. 2018 Dec;4(4):712-716. doi: 10.21037/jss.2018.11.02.

Abstract

BACKGROUND

The objective of this study is to demonstrate the epidemiology and trends in management of patients with central cord syndrome (CCS) who present to the emergency department. Recent literature has reported that surgical treatment for CCS have increased over the previous decades.

METHODS

The National Emergency Department Sample (NEDS) was queried from 2009 through 2012 to generate national estimates of patients who presented to the emergency department in the United States and were diagnosed with CCS.

RESULTS

From 2009 through 2012, there were 11,975 emergency room visits for CCS (mean age 60 years). The two most common injury mechanisms were: fall (55%) and motor vehicle accident (15%). Concomitant cervical fractures were found in 10% patients. Ninety-three percent of patients were admitted to the hospital directly or after transfer to another facility, and 7% were discharged home. Fifty-five percent of patients were treated non-operatively, 39% were treated with cervical fusion surgery and 6% were treated with laminoplasty. Of patients who underwent cervical fusion, 62% received anterior decompression and fusion, 32% received posterior decompression and fusion, and 6% received combined anterior-posterior decompression and fusion. The incidence of in-hospital mortality was 2.6%. Mortality was associated with older patient age (OR 1.06, P<0.001) and greater comorbidities (OR 1.72, P<0.001).

CONCLUSIONS

Majority of patients who presented to the emergency room for CCS in the United States were treated non-operatively. Advanced age and greater comorbidities were the factors that were most associated with increased risk of in-hospital mortality in patients with CCS.

摘要

背景

本研究的目的是阐述急诊就诊的中央脊髓综合征(CCS)患者的流行病学特征及治疗趋势。近期文献报道,在过去几十年中,CCS的手术治疗有所增加。

方法

查询2009年至2012年的美国国家急诊科样本(NEDS),以得出美国急诊科就诊且被诊断为CCS患者的全国性估计数据。

结果

2009年至2012年期间,因CCS急诊就诊的患者有11,975例(平均年龄60岁)。两种最常见的损伤机制为:跌倒(55%)和机动车事故(15%)。10%的患者伴有颈椎骨折。93%的患者直接入院或转至其他机构后入院,7%的患者出院回家。55%的患者接受非手术治疗,39%的患者接受颈椎融合手术,6%的患者接受椎板成形术。在接受颈椎融合手术的患者中,62%接受前路减压融合术,32%接受后路减压融合术,6%接受前后路联合减压融合术。住院死亡率为2.6%。死亡率与患者年龄较大(比值比1.06,P<0.001)和合并症较多(比值比1.72,P<0.001)相关。

结论

在美国,因CCS到急诊室就诊的大多数患者接受非手术治疗。高龄和更多合并症是与CCS患者住院死亡风险增加最相关的因素。

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