Praxis für Neurologie und Psychiatrie, Berlin, Germany.
Epidemiology, IQVIA, Frankfurt, Germany.
J Alzheimers Dis. 2019;67(4):1313-1318. doi: 10.3233/JAD-181180.
The diagnosis of mild cognitive impairment (MCI) is becoming increasingly important for the medical treatment of dementia.
The aim of this study was to investigate whether the coded prevalence of MCI changed in the period from 2007 to 2017 compared to dementia diagnoses.
This was a retrospective evaluation of diagnostic data from 432 general practitioner (GP) practices and 53 neuropsychiatrist (NP) practices in Germany based on the Disease Analyzer database (IQVIA). The frequencies with which MCI and dementia were diagnosed in these practices were determined. The frequency with which dementia was diagnosed was included to determine whether the change in the frequency of MCI diagnoses was due to the increase in dementia prevalence.
It was found that the number of GP practices with patients receiving MCI diagnoses increased from 16% to 46%, while the number of NP practices with patients receiving MCI diagnoses increased from 55% to 75%. Moreover, the study found an increase in the coded prevalence of MCI from 0.4 to 1.9 patients/GP practice and from 6.5 to 11.1 patients/NP practice were observed.
A growing number of GPs and NPs code MCI with increasing frequency. However, the coding frequency of MCI in 2017 corresponded to less than 10% of its true prevalence. A sharp increase in MCI diagnoses can be expected, along with the establishment of preventive and disease-modifying dementia strategies.
轻度认知障碍 (MCI) 的诊断对于痴呆症的治疗变得越来越重要。
本研究旨在调查与痴呆症诊断相比,2007 年至 2017 年期间 MCI 的编码患病率是否发生了变化。
这是对德国 432 家全科医生 (GP) 诊所和 53 家神经精神病学 (NP) 诊所基于疾病分析器数据库 (IQVIA) 的诊断数据的回顾性评估。确定这些诊所中 MCI 和痴呆症的诊断频率。纳入痴呆症的诊断频率,以确定 MCI 诊断频率的变化是否归因于痴呆症患病率的增加。
发现接受 MCI 诊断的 GP 诊所数量从 16%增加到 46%,而接受 MCI 诊断的 NP 诊所数量从 55%增加到 75%。此外,研究发现 MCI 的编码患病率从每 GP 诊所 0.4 例增加到 1.9 例,从每 NP 诊所 6.5 例增加到 11.1 例。
越来越多的全科医生和神经科医生越来越频繁地对 MCI 进行编码。然而,2017 年 MCI 的编码频率还不到其真实患病率的 10%。预计 MCI 诊断会急剧增加,同时也会制定预防和改变疾病的痴呆症策略。