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一项关于自闭症谱系障碍儿童康复长期效果的随访研究。

A follow-up study on the long-term effects of rehabilitation in children with autism spectrum disorders.

作者信息

Zhang Lili, Liu Yimei, Zhou Ziyun, Wei Yan, Wang Jie, Yang Jie, Wu Yanling, Sun Yan

机构信息

Department of Child Healthcare, Wuxi Children's Hospital, Wuxi, Jiangsu, P.R. China.

出版信息

NeuroRehabilitation. 2019;44(1):1-7. doi: 10.3233/NRE-182502.

Abstract

BACKGROUND

Autism spectrum disorders are complex neurodevelopmental disorders. Early intervention training is a very important treatment strategy. Under the current background of rehabilitation supply in China, the long-term efficacy of intervention is unexplored.

OBJECTIVE

This study aimed to investigate the effects of long-term rehabilitation and related factors affecting the recovery of autistic children.

METHODS

A total of 137 autistic children were followed up for 3 years. They received two neuropsychological assessments at the first visit and 3 years after referral. Assessments included Childhood Autism Rating Scale (CARS), Autism Behavior Checklist (ABC), and Developmental Diagnostic Scale of Children Aged 0-6 Years. All children were asked to visit rehabilitation centers for rehabilitation training. In the study, 105 children with autism spectrum disorders (ASD) received rehabilitation training according to the physician's orders (the rehabilitation group), and 32 patients did not receive rehabilitation training (the nonrehabilitation group).

RESULTS

The ABC, CARS, and developmental quotient scores of the rehabilitation group were statistically significant between initial assessment and reassessment. No significant difference was observed in the nonrehabilitation group.

CONCLUSIONS

Rehabilitation training significantly improved the core symptoms and cognitive function in children with ASD, exerting a long-term rehabilitation effect. The initial language development quotient, children's training time, and parental participation time of autistic children significantly impacted the change in ABC.

摘要

背景

自闭症谱系障碍是复杂的神经发育障碍。早期干预训练是一种非常重要的治疗策略。在中国当前康复供给的背景下,干预的长期疗效尚未得到探索。

目的

本研究旨在探讨长期康复对自闭症儿童的影响以及影响其康复的相关因素。

方法

对137名自闭症儿童进行了3年的随访。他们在首次就诊时和转诊3年后接受了两次神经心理学评估。评估包括儿童自闭症评定量表(CARS)、自闭症行为检查表(ABC)和0 - 6岁儿童发育诊断量表。所有儿童均被要求到康复中心进行康复训练。在研究中,105名自闭症谱系障碍(ASD)儿童按照医嘱接受康复训练(康复组),32名患者未接受康复训练(非康复组)。

结果

康复组的ABC、CARS和发育商得分在初始评估和重新评估之间有统计学意义。非康复组未观察到显著差异。

结论

康复训练显著改善了ASD儿童的核心症状和认知功能,发挥了长期的康复效果。自闭症儿童的初始语言发育商、儿童训练时间和家长参与时间对ABC的变化有显著影响。

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