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一种保留种植体部位活力并增强骨生成的新型截骨术制备技术。

A Novel Osteotomy Preparation Technique to Preserve Implant Site Viability and Enhance Osteogenesis.

作者信息

Chen Chih-Hao, Coyac Benjamin R, Arioka Masaki, Leahy Brian, Tulu U Serdar, Aghvami Maziar, Holst Stefan, Hoffmann Waldemar, Quarry Antony, Bahat Oded, Salmon Benjamin, Brunski John B, Helms Jill A

机构信息

Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA 94305, USA.

Craniofacial Research Center, Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University School of Medicine, Taoyuan 33305, Taiwan.

出版信息

J Clin Med. 2019 Feb 1;8(2):170. doi: 10.3390/jcm8020170.

DOI:10.3390/jcm8020170
PMID:30717291
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6406409/
Abstract

The preservation of bone viability at an osteotomy site is a critical variable for subsequent implant osseointegration. Recent biomechanical studies evaluating the consequences of site preparation led us to rethink the design of bone-cutting drills, especially those intended for implant site preparation. We present here a novel drill design that is designed to efficiently cut bone at a very low rotational velocity, obviating the need for irrigation as a coolant. The low-speed cutting produces little heat and, consequently, osteocyte viability is maintained. The lack of irrigation, coupled with the unique design of the cutting flutes, channels into the osteotomy autologous bone chips and osseous coagulum that have inherent osteogenic potential. Collectively, these features result in robust, new bone formation at rates significantly faster than those observed with conventional drilling protocols. These preclinical data have practical implications for the clinical preparation of osteotomies and alveolar bone reconstructive surgeries.

摘要

截骨部位骨活力的保存是后续种植体骨整合的关键变量。最近评估手术部位准备后果的生物力学研究促使我们重新思考骨切割钻的设计,尤其是那些用于种植体部位准备的钻。我们在此展示一种新颖的钻设计,其旨在以非常低的转速高效切割骨,从而无需使用冲洗液作为冷却剂。低速切割产生的热量极少,因此,骨细胞活力得以维持。无需冲洗,再加上切割槽的独特设计,会将具有内在成骨潜力的自体骨屑和骨凝块导入截骨部位。总体而言,这些特性导致强健的新骨形成,其速度明显快于传统钻孔方案所观察到的速度。这些临床前数据对截骨术的临床准备和牙槽骨重建手术具有实际意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/761be383ecbc/jcm-08-00170-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/a03198210553/jcm-08-00170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/d69cb190bf99/jcm-08-00170-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/12ba162071ec/jcm-08-00170-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/761be383ecbc/jcm-08-00170-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/a03198210553/jcm-08-00170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/d69cb190bf99/jcm-08-00170-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/12ba162071ec/jcm-08-00170-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2a5/6406409/761be383ecbc/jcm-08-00170-g004.jpg

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1
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J Dent Res. 2019 Apr;98(4):450-458. doi: 10.1177/0022034518818456. Epub 2019 Jan 9.
2
A Thermal and Biological Analysis of Bone Drilling.骨钻孔的热学与生物学分析
J Biomech Eng. 2018 Oct 1;140(10):1010101-8. doi: 10.1115/1.4040312.
3
An osteopenic/osteoporotic phenotype delays alveolar bone repair.骨质疏松/骨量减少表型延迟牙槽骨修复。
BMC Oral Health. 2025 May 28;25(1):830. doi: 10.1186/s12903-025-06179-9.
4
Comparative Analysis of the Histological Characteristics of Bone Tissue Following Implant Drill Preparation Under Various Parameters: An In Vitro Study.不同参数下种植体钻孔制备后骨组织组织学特征的比较分析:一项体外研究
J Clin Med. 2025 Mar 21;14(7):2161. doi: 10.3390/jcm14072161.
5
Oral cell lysates reduce osteoclastogenesis in murine bone marrow cultures.口腔细胞裂解物可减少小鼠骨髓培养物中的破骨细胞生成。
Cytotechnology. 2025 Feb;77(1):39. doi: 10.1007/s10616-024-00688-1. Epub 2025 Jan 8.
6
Biomechanical Basis for Bone Healing and Osseointegration of Implants in Sinus Grafts.窦提升植骨术中骨愈合及种植体骨结合的生物力学基础
Clin Implant Dent Relat Res. 2025 Feb;27(1):e13424. doi: 10.1111/cid.13424. Epub 2024 Dec 5.
7
In Vitro Bioassay for Damage-Associated Molecular Patterns Arising from Injured Oral Cells.受损口腔细胞产生的损伤相关分子模式的体外生物测定
Bioengineering (Basel). 2024 Jul 5;11(7):687. doi: 10.3390/bioengineering11070687.
8
Determination of Osteoblast Cell Viability and Histological Changes of Samples Obtained from Different Implant Drills during Osteotomy.截骨术中不同种植钻获取样本的成骨细胞活力测定及组织学变化
J Dent (Shiraz). 2023 Jun;24(2):220-225. doi: 10.30476/dentjods.2022.91439.1579.
9
Design modification of surgical drill bit for final osteotomy site preparation towards improved bone-implant contact.用于最终截骨部位准备的手术钻头的设计改进,以改善骨与植入物的接触。
Heliyon. 2023 May 26;9(6):e16451. doi: 10.1016/j.heliyon.2023.e16451. eCollection 2023 Jun.
10
Oral Cell Lysates Reduce the Inflammatory Response of Activated Macrophages.口腔细胞裂解物可降低活化巨噬细胞的炎症反应。
J Clin Med. 2023 Feb 20;12(4):1701. doi: 10.3390/jcm12041701.
Bone. 2018 Jul;112:212-219. doi: 10.1016/j.bone.2018.04.019. Epub 2018 Apr 25.
4
A WNT protein therapeutic improves the bone-forming capacity of autografts from aged animals.一种 WNT 蛋白治疗药物可提高老年动物自体移植物的成骨能力。
Sci Rep. 2018 Jan 8;8(1):119. doi: 10.1038/s41598-017-18375-x.
5
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J Dent Res. 2018 Apr;97(4):451-459. doi: 10.1177/0022034517742631. Epub 2017 Dec 4.
6
Biophysical regulation of osteotomy healing: An animal study.骨切开术愈合的生物物理调节:一项动物研究。
Clin Implant Dent Relat Res. 2017 Aug;19(4):590-599. doi: 10.1111/cid.12499. Epub 2017 Jun 13.
7
Relationships among Bone Quality, Implant Osseointegration, and Wnt Signaling.骨质量、种植体骨整合与Wnt信号传导之间的关系
J Dent Res. 2017 Jul;96(7):822-831. doi: 10.1177/0022034517700131. Epub 2017 Mar 22.
8
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J Dent Res. 2017 Jul;96(8):909-916. doi: 10.1177/0022034517707513. Epub 2017 May 8.
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J Dent Res. 2017 Apr;96(4):413-420. doi: 10.1177/0022034516683932. Epub 2017 Jan 3.
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Mediators Inflamm. 2016;2016:5319718. doi: 10.1155/2016/5319718. Epub 2016 Sep 22.