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花生过敏管理。

Management of Peanut Allergy.

机构信息

Section of Allergy and Immunology, Children's Hospital Colorado, Food Challenge and Research Unit, University of Colorado School of Medicine, Aurora, Colo; The David Hide Asthma and Allergy Research Centre, Newport, Isle of Wight, United Kingdom.

Division of Pediatric Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai and the Jafee Food Allergy Institute, New York, NY.

出版信息

J Allergy Clin Immunol Pract. 2019 Feb;7(2):345-355.e2. doi: 10.1016/j.jaip.2018.10.043.

Abstract

Peanut allergy is a growing public health concern in westernized countries. Peanut allergy is characterized as an often severe and lifelong allergy, which can have detrimental effects on quality of life and trigger anxiety. Although multiple therapeutic options are emerging, the focus of current management strategies is strict peanut avoidance and carriage of self-injectable epinephrine. The greatest risk of reacting to peanut comes from direct ingestion, whereas casual skin contact or airborne exposure is highly unlikely to provoke significant symptoms. Patients and families must be educated about how to best execute strict peanut avoidance through careful label reading as well as how to understand and address likely and unlikely risk with regard to peanut exposure in public, in particular when dining outside of the home and for children attending school or child care. This review discusses the risk of exposure in public such as at school or on an airplane and how such risk can be abated, situations and scenarios when dining out of the house that may pose more risks than others, the essentials of US and EU label reading laws with particular emphasis on precautionary labeling and the risk implied by such, quality of life and psychosocial issues that may affect the peanut allergic individual and family, and a discussion of how risk may differ and evolve based on the patient's age.

摘要

花生过敏是西方国家日益严重的公共卫生问题。花生过敏的特点是一种经常严重且终生的过敏,会对生活质量产生不利影响,并引发焦虑。尽管出现了多种治疗选择,但当前管理策略的重点是严格避免食用花生和携带自我注射肾上腺素。对花生产生反应的最大风险来自直接摄入,而偶然的皮肤接触或空气传播暴露极不可能引发明显症状。必须教育患者及其家属如何通过仔细阅读标签来最好地执行严格的花生回避,以及如何理解和应对公共场合(特别是在家以外的地方用餐时)和儿童上学或入托时与花生接触的可能和不太可能的风险。这篇综述讨论了在公共场所(如学校或飞机上)暴露的风险,以及如何减轻这种风险,在外面用餐时可能比其他情况更具风险的情况和场景,美国和欧盟标签阅读法规的要点,特别是关于预防性标签以及由此带来的风险,可能影响花生过敏个体和家庭的生活质量和心理社会问题,以及讨论风险如何根据患者的年龄而有所不同和演变。

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