Emory University School of Medicine, Atlanta, Ga.
Sagamihara National Hospital, Sagamihara, Japan.
J Allergy Clin Immunol Pract. 2019 Feb;7(2):357-365. doi: 10.1016/j.jaip.2018.11.049.
Based on productive translational research programs conducted over the last 20 years, the clinical landscape of peanut allergy is now rapidly changing. In this review, we review data from recent trials of investigational peanut oral and epicutaneous immunotherapies, explore the pipeline of novel therapies in early development, and identify future research needs and priorities.
基于过去 20 年开展的富有成效的转化研究计划,花生过敏的临床格局正在迅速改变。在这篇综述中,我们回顾了最近关于研究性花生口服和皮内免疫疗法的试验数据,探讨了早期开发的新型疗法的研发管道,并确定了未来的研究需求和重点。