URZ, Unité de Recherches Zootechniques INRA, 97170, Petit-Bourg, Guadeloupe, France.
PTEA, Plateforme d'Expérimentation sur l'Animal INRA, 97170, Petit-Bourg, Guadeloupe, France.
Sci Rep. 2019 Feb 4;9(1):1237. doi: 10.1038/s41598-018-37800-3.
Resistance to gastro-intestinal nematode (GIN) in small ruminant is expected to arise from protein-rich rather than from energy-rich feeds. The objective of this study was to investigate the effect of the quality of the dietary proteins on the response of Creole goats to Haemonchus contortus. Three diets were compared: no supplementation (Hay: hay ad libitum), Control supplement (CS: hay ad libitum +2% BW of CS at 70 g of by-pass proteins/kg) and supplement enriched in rumen-protected proteins (RPP: hay ad libitum +2% BW of RPP at 139 g of by-pass proteins/kg). The FEC (faecal eggs counts) and the TFEC (total faecal eggs excreted/day) were significantly lower in the RPP. No difference was found between the supplemented diets for the total number of nematodes, but the RPP reduced the parasite prolificacy. The highest IgA responses were observed in animals with the highest nematode burden (Hay compared with CS diets). However, while the FEC and the TFEC were lower in animals feed with the RPP the IgA response were similar to those of the Hay. The IgA response that control GIN egg production in sheep could be one mediator of the resistance to H. contortus induced with by-pass proteins in goats.
反刍动物对胃肠道线虫（GIN）的抗性预计将来自富含蛋白质的饲料，而不是富含能量的饲料。本研究的目的是研究日粮蛋白质量对克里奥尔山羊对捻转血矛线虫反应的影响。比较了三种日粮：不补充（干草：自由采食干草）、对照补充（CS：自由采食干草+70g 过瘤胃蛋白/ BW 的 CS）和富含保护性瘤胃蛋白的补充料（RPP：自由采食干草+139g 过瘤胃蛋白/ BW 的 RPP）。RPP 组的 FEC（粪便卵计数）和 TFEC（每日总粪便卵排出量）明显降低。补充料组的总线虫数量没有差异，但 RPP 降低了寄生虫繁殖力。具有最高线虫负荷的动物（干草与 CS 日粮相比）观察到最高的 IgA 反应。然而，尽管 RPP 喂养的动物的 FEC 和 TFEC 较低，但 IgA 反应与干草相似。控制绵羊 GIN 产卵的 IgA 反应可能是通过过瘤胃蛋白诱导的山羊捻转血矛线虫抗性的一种介导物。
