Gjerris A, Praestholm J, Klinken L
Neuroradiology. 1978 Apr 27;15(2):79-84. doi: 10.1007/BF00334119.
Cerebral ventriculography was performed on adult albino rats to compare the effect of metrizamide and iodophendylate on the ependymal wall. The animals were killed by vascular perfusion 1 month and 4 months after ventriculography. The ependymal layer and the underlying brain tissue were examined with the electron microscope. After the use of metrizamide the tissue appeared completely normal. The use of iodophendylate provoked accumulation of phagocytozing macrophages on the ependymal wall and storage of iodophendylate in the ependyma and underlying brain tissue. These changes were present both 1 and 4 months after ventriculography.
对成年白化大鼠进行脑室造影，以比较甲泛葡胺和碘苯酯对室管膜壁的影响。脑室造影后1个月和4个月，通过血管灌注处死动物。用电子显微镜检查室管膜层和其下的脑组织。使用甲泛葡胺后，组织看起来完全正常。使用碘苯酯会引起吞噬性巨噬细胞在室管膜壁上积聚，以及碘苯酯在室管膜和其下脑组织中的蓄积。这些变化在脑室造影后1个月和4个月时均存在。
