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子宫移植的新进展:新的情况和未来的影响。

Advancements in uterus transplant: new scenarios and future implications.

机构信息

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Rome, Italy.

出版信息

Eur Rev Med Pharmacol Sci. 2019 Jan;23(2):892-902. doi: 10.26355/eurrev_201901_16904.

DOI:10.26355/eurrev_201901_16904
PMID:30720198
Abstract

Women suffering from Uterine Factor Infertility (UFI) arising from congenital conditions (e.g., Rokitansky-Kuster-Hauser syndrome) or hysterectomy can fulfill their wish to achieve motherhood only by resorting to surrogacy, which is, however, banned in most countries. Medical research has long been looking into uterus transplant (UTx), which may constitute a valuable alternative for such patients. Following decades of animal testing and clinical trials, several successful pregnancies have been carried to term. Yet UTx is still to be considered as an experimental procedure. The report's authors believe UTx has the potential to become a mainstream surgical practice, but for the time being, several ethical issues need to be weighed in before it does.

摘要

因先天性疾病(如罗基坦斯基-库斯特-豪泽综合征)或子宫切除术而患有子宫因素不孕(Uterine Factor Infertility,UFI)的女性,只有通过代孕才能实现生育愿望,但代孕在大多数国家都是被禁止的。医学研究长期以来一直在研究子宫移植(Uterus Transplant,UTx),这可能为这些患者提供了一种有价值的选择。经过几十年的动物试验和临床试验,已经有几例成功妊娠至足月。然而,UTx 仍被视为一种实验性手术。报告的作者认为,UTx 有可能成为一种主流的手术实践,但目前,在实施之前,需要权衡一些伦理问题。

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1
Advancements in uterus transplant: new scenarios and future implications.子宫移植的新进展:新的情况和未来的影响。
Eur Rev Med Pharmacol Sci. 2019 Jan;23(2):892-902. doi: 10.26355/eurrev_201901_16904.
2
The Interest of Women with Mayer-Rokitansky-Küster-Hauser Syndrome and Laparoscopic Vecchietti Neovagina in Uterus Transplantation.患有迈耶-罗基坦斯基-库斯特-豪泽综合征且接受腹腔镜韦基耶蒂新阴道成形术的女性对子宫移植的兴趣。
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Perception of having children through surrogacy in individuals with MRKH in Vietnam: a qualitative study.越南先天性无阴道综合征患者对代孕生育子女的认知:一项定性研究
Front Psychol. 2024 May 6;15:1372405. doi: 10.3389/fpsyg.2024.1372405. eCollection 2024.
2
The Ethical Implications of Tissue Engineering for Regenerative Purposes: A Systematic Review.组织工程用于再生目的的伦理影响:系统评价。
Tissue Eng Part B Rev. 2023 Apr;29(2):167-187. doi: 10.1089/ten.TEB.2022.0033. Epub 2022 Oct 20.
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Information obligation in surgery.手术中的信息告知义务。
Acta Biomed. 2021 Sep 2;92(4):e2021072. doi: 10.23750/abm.v92i4.10318.
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Operative and Clinical Outcomes of Minimally Invasive Living-Donor Surgery on Uterus Transplantation: A Literature Review.子宫移植微创活体供体手术的手术及临床结果:文献综述
J Clin Med. 2021 Jan 18;10(2):349. doi: 10.3390/jcm10020349.
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Surrogacy and "Procreative Tourism". What Does the Future Hold from the Ethical and Legal Perspectives?代孕与“生育旅游”。从伦理和法律角度看未来会怎样?
Medicina (Kaunas). 2021 Jan 8;57(1):47. doi: 10.3390/medicina57010047.