Department of Restorative Dentistry, University of Illinois at Chicago, College of Dentistry, Chicago, IL.
Department of Chemical Engineering, University of Illinois at Chicago, Chicago, IL.
J Prosthodont. 2019 Dec;28(9):1011-1017. doi: 10.1111/jopr.13032. Epub 2019 Feb 20.
The objective of this study was to improve the surface characteristics of poly (methyl methacrylate) (PMMA) by developing a novel, thin film coating process and to characterize the resulting coated surface.
An atomic layer deposition (ALD) technique was developed to deposit a titanium dioxide (TiO ) nano-thin film on PMMA. The surface wettability for both coated and uncoated PMMA was determined by measuring water contact angle. Wear resistance was assessed using a mechanical tooth-brushing device with a 50 g load for 6000 strokes after 5 months of water storage. A denture cleanser challenge test was performed by using sonication in 3.8% sodium perborate for 1 hour with aged specimens. X-ray photoelectron spectroscopy (XPS) was used before and after the brushing test and challenge test to analyze the PMMA surface chemical composition. The mechanical strength of coated and uncoated PMMA was measured using a three-point bending test. Surface microbial interactions were also evaluated by assessing Candida albicans biofilm attachment.
Nano-TiO coating (30 nm thick) was successfully deposited on PMMA at 65°C. After coating, water contact angle decreased from 70° to less than 5°. After brushing test, the coating remained intact. XPS analysis revealed no loss of TiO from coated specimens following brushing and denture cleanser sonication for 1 hour. There was no statistically significant difference in mechanical strength (MPa) (mean ± SD) between PMMA (139.4 ± 11.3) and TiO -PMMA (160.7 ± 37.1) (p = 0.0995). C. albicans attachment decreased by 63% to 77% on the coated PMMA surface.
ALD is a promising technique to modify surface properties of PMMA and resulted in a stable adherent thin film. By depositing a TiO coating, PMMA surface properties may lead to significantly reduced microorganism adhesion and easier pathogen removal from PMMA. For patients who wear dentures, reducing the oral microbial biofilm burden using a TiO -coated PMMA surface could positively impact their oral and systemic health.
本研究旨在通过开发一种新型的薄膜涂覆工艺来改善聚甲基丙烯酸甲酯（PMMA）的表面特性，并对所得涂覆表面进行表征。
采用原子层沉积（ALD）技术在 PMMA 上沉积一层二氧化钛（TiO ）纳米薄膜。通过测量水接触角来确定涂覆和未涂覆 PMMA 的表面润湿性。在 5 个月的水储存后，使用带有 50g 负载的机械牙刷装置进行 6000 次刷牙，评估耐磨性。通过在 3.8%过硼酸钠中进行 1 小时的超声处理，对老化标本进行义齿清洁剂挑战测试。在刷牙测试和挑战测试前后，使用 X 射线光电子能谱（XPS）分析 PMMA 表面化学成分。使用三点弯曲试验测量涂覆和未涂覆 PMMA 的机械强度。还通过评估白色念珠菌生物膜附着来评估表面微生物相互作用。
在 65°C 成功将纳米 TiO 涂层（30nm 厚）沉积在 PMMA 上。涂覆后，水接触角从 70°降至小于 5°。经过刷牙测试后，涂层保持完整。XPS 分析表明，经过 1 小时的刷牙和义齿清洁剂超声处理后，涂覆的样本中没有 TiO 的损失。PMMA（139.4 ± 11.3）和 TiO -PMMA（160.7 ± 37.1）之间的机械强度（MPa）（平均值 ± SD）无统计学差异（p = 0.0995）。在涂覆 PMMA 表面上，白色念珠菌的附着减少了 63%至 77%。
ALD 是一种很有前途的技术，可以改变 PMMA 的表面特性，并形成稳定的附着薄膜。通过沉积 TiO 涂层，PMMA 表面特性可能会导致微生物附着显著减少，并且更容易从 PMMA 上清除病原体。对于佩戴义齿的患者，使用涂覆 TiO 的 PMMA 表面减少口腔微生物生物膜负担可能会对其口腔和全身健康产生积极影响。
