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口腔疾病的先进材料与技术

Advanced materials and technologies for oral diseases.

作者信息

Cui Hao, You Yan, Cheng Guo-Wang, Lan Zhou, Zou Ke-Long, Mai Qiu-Ying, Han Yan-Hua, Chen Hao, Zhao Yu-Yue, Yu Guang-Tao

机构信息

Stomatological Hospital, Southern Medical University, Guangzhou, China.

Science and Technology Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Sci Technol Adv Mater. 2023 Jan 4;24(1):2156257. doi: 10.1080/14686996.2022.2156257. eCollection 2023.

DOI:10.1080/14686996.2022.2156257
PMID:36632346
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9828859/
Abstract

Oral disease, as a class of diseases with very high morbidity, brings great physical and mental damage to people worldwide. The increasing burden and strain on individuals and society make oral diseases an urgent global health problem. Since the treatment of almost all oral diseases relies on materials, the rapid development of advanced materials and technologies has also promoted innovations in the treatment methods and strategies of oral diseases. In this review, we systematically summarized the application strategies in advanced materials and technologies for oral diseases according to the etiology of the diseases and the comparison of new and old materials. Finally, the challenges and directions of future development for advanced materials and technologies in the treatment of oral diseases were refined. This review will guide the fundamental research and clinical translation of oral diseases for practitioners of oral medicine.

摘要

口腔疾病作为一类发病率极高的疾病，给全球范围内的人们带来了巨大的身心损害。个人和社会日益加重的负担与压力使口腔疾病成为一个亟待解决的全球健康问题。由于几乎所有口腔疾病的治疗都依赖材料，先进材料和技术的快速发展也推动了口腔疾病治疗方法和策略的创新。在本综述中，我们根据疾病的病因以及新旧材料的对比，系统总结了先进材料和技术在口腔疾病中的应用策略。最后，提炼了先进材料和技术在口腔疾病治疗方面未来发展面临的挑战和方向。本综述将为口腔医学从业者指导口腔疾病的基础研究和临床转化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/396d/9828859/ab9a8698bff6/TSTA_A_2156257_F0012_OC.jpg
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4
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