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土木香(Turcz.)Baill. 在人类健康和营养中的潜力:对现有知识和治疗观点的综述。

Potential of (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives.

机构信息

Institute of Fermentation Technology and Microbiology, Lodz University of Technology, Wolczanska 171/173, 90-924 Lodz, Poland.

Institute of Technical Biochemistry, Lodz University of Technology, Stefanowskiego 4/10, 90-924 Lodz, Poland.

出版信息

Nutrients. 2019 Feb 4;11(2):333. doi: 10.3390/nu11020333.

DOI:10.3390/nu11020333
PMID:30720717
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6412213/
Abstract

(Turcz.) Baill. (SCE) is a plant with high potential for beneficial health effects, confirmed by molecular studies. Its constituents exert anti-cancer effects through the induction of cell cycle arrest and apoptosis, as well as inhibition of invasion and metastasis in cancer cell lines and experimental animals. SCE displays antimicrobial effects against several pathogenic strains. It has anti-diabetic potential, supported by hypoglycemic activity. A diet rich in SCE improves pancreatic functions, stimulates insulin secretion, and reduces complications in diabetic animals. SCE prevents lipid accumulation and differentiation of preadipocytes, indicating its anti-obesity potential. SCE exerts a protective effect against skin photoaging, osteoarthritis, sarcopenia, senescence, and mitochondrial dysfunction, and improves physical endurance and cognitive/behavioural functions, which can be linked with its general anti-aging potency. In food technology, SCE is applied as a preservative, and as an additive to increase the flavour, taste, and nutritional value of food. In summary, SCE displays a variety of beneficial health effects, with no side effects. Further research is needed to determine the molecular mechanisms of SCE action. First, the constituents responsible for its beneficial effects should be isolated and identified, and recommended as preventative nutritional additives, or considered as therapeutics.

摘要

(Turcz.)Baill.(SCE)是一种具有潜在有益健康作用的植物,这一作用已得到分子研究的证实。其成分通过诱导细胞周期停滞和细胞凋亡,以及抑制癌细胞系和实验动物的侵袭和转移,发挥抗癌作用。SCE 对几种病原菌具有抗菌作用。它具有抗糖尿病作用,这一作用得到了降血糖活性的支持。富含 SCE 的饮食可改善胰腺功能,刺激胰岛素分泌,并减少糖尿病动物的并发症。SCE 可防止脂肪在前期脂肪细胞中的积累和分化,表明其具有抗肥胖作用。SCE 对皮肤光老化、骨关节炎、肌肉减少症、衰老和线粒体功能障碍具有保护作用,并可提高身体耐力和认知/行为功能,这与它的整体抗衰老能力有关。在食品技术中,SCE 可用作防腐剂,并可作为添加剂来增加食品的风味、口感和营养价值。总之,SCE 具有多种有益健康的作用,且无副作用。需要进一步的研究来确定 SCE 作用的分子机制。首先,应分离和鉴定出其有益作用的成分,并将其推荐为预防性营养添加剂,或作为治疗药物。

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