Meng Ye, Qiang Wenjiang, Pang Jingqin
School of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.
National Demonstration Center for Experimental Materials Education, University of Science and Technology Beijing, Beijing 100083, China.
Materials (Basel). 2019 Feb 4;12(3):484. doi: 10.3390/ma12030484.
Hydroxyapatite (HAP) has excellent biocompatibility with living bone tissue and does not cause defensive body reactions, therefore, it has become one of the most widely used calcium phosphate materials in dental and medical fields. However, its poor mechanical properties have been a substantial challenge in the application of HAP for the replacement of load-bearing or large bone defects. Laminated HAP⁻45S5 bioglass ceramics composites were prepared by the spark plasma sintering (SPS) technique. The interface structures between the HAP and 45S5 bioglass layers and the mechanical properties of the laminated composites were investigated. It was demonstrated that there was mutual transfer and exchange of Ca and Na atoms at the interface between 45S5 bioglass/HAP laminated layers, which contributed considerably to the interfacial bonding. Due from the laminated structure and strong interface bonding, laminated HAP⁻45S5 bioglass is recommended for structural applications.
羟基磷灰石（HAP）与活骨组织具有优异的生物相容性，不会引起机体防御反应，因此，它已成为牙科和医学领域应用最广泛的磷酸钙材料之一。然而，其较差的力学性能一直是HAP应用于替代承重或大骨缺损的一大挑战。采用放电等离子烧结（SPS）技术制备了层状HAP⁻45S5生物玻璃陶瓷复合材料。研究了HAP与45S5生物玻璃层之间的界面结构以及层状复合材料的力学性能。结果表明，在45S5生物玻璃/HAP层状界面处存在Ca和Na原子的相互转移和交换，这对界面结合有很大贡献。由于层状结构和强界面结合，推荐层状HAP⁻45S5生物玻璃用于结构应用。
