Core Concept: Solving Peto's Paradox to better understand cancer.
作者信息
Callier Viviane
出版信息
Proc Natl Acad Sci U S A. 2019 Feb 5;116(6):1825-1828. doi: 10.1073/pnas.1821517116.
Abstract
摘要
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How to Make a Rodent Giant: Genomic Basis and Tradeoffs of Gigantism in the Capybara, the World's Largest Rodent.如何培育巨型啮齿动物：水豚——世界上最大的啮齿动物——巨型化的基因组基础和权衡。
Mol Biol Evol. 2021 May 4;38(5):1715-1730. doi: 10.1093/molbev/msaa285.
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Size matters: height, cell number and a person's risk of cancer.大小很重要：身高、细胞数量与一个人罹患癌症的风险。
Proc Biol Sci. 2018 Oct 24;285(1889):20181743. doi: 10.1098/rspb.2018.1743.
3
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Growing old, yet staying young: The role of telomeres in bats' exceptional longevity.衰老，却保持年轻：端粒在蝙蝠非凡的长寿中的作用。
Sci Adv. 2018 Feb 7;4(2):eaao0926. doi: 10.1126/sciadv.aao0926. eCollection 2018 Feb.
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copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants.拷贝数扩增与大象体型增大的进化以及增强的DNA损伤反应有关。
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