John Walsh Centre for Rehabilitation Research, Sydney Medical School, University of Sydney, Sydney, Australia.
Spinal Cord. 2019 Jun;57(6):449-460. doi: 10.1038/s41393-019-0242-z. Epub 2019 Feb 5.
A systematic review.
The aim of this review was to determine the effectiveness of physiotherapy (PT) interventions for increasing voluntary muscle strength in people with spinal cord injuries (SCI).
We included randomised controlled trials of PT interventions for people with SCI. We were interested in two comparisons: PT interventions compared with sham or no intervention, and PT interventions compared to each other. The outcome of interest was voluntary strength of muscles directly affected by SCI. All included studies were rated according to the Cochrane Risk of Bias Tool and results of similar trials were pooled using meta-analyses where possible.
Twenty-six trials met the inclusion criteria and provided useable data. A statistically significant between-group difference was found in four comparisons, namely, resistance training versus no intervention (standardised mean difference (SMD) = 0.64; 95% CI, 0.22-1.07; p = 0.003); resistance training combined with electrical stimulation versus no intervention (mean difference (MD) = 14 Nm; 95% CI, 1-27; p = 0.03); a package of PT interventions versus no intervention (MD = 4.8/50 points on the Lower Extremity Motor Score (LEMS); 95% CI 1.9-7.7; p = 0.01); and robotic gait training versus overground gait training (MD = 3.1/50 points on the LEMS; 95% CI, 1.3-5.0; p = 0.0008).
There is evidence that a small number of PT interventions increase voluntary strength in muscles directly affected by SCI.
系统评价。
本综述旨在确定物理治疗(PT)干预措施在提高脊髓损伤(SCI)患者的自主肌肉力量方面的有效性。
我们纳入了针对 SCI 患者的 PT 干预措施的随机对照试验。我们对两种比较感兴趣:PT 干预与假对照或无干预的比较,以及 PT 干预之间的比较。感兴趣的结局是 SCI 直接影响的肌肉的自主力量。所有纳入的研究均根据 Cochrane 偏倚风险工具进行评估,如有可能,使用荟萃分析对相似试验的结果进行汇总。
26 项试验符合纳入标准并提供了可用数据。四项比较中有统计学意义的组间差异,即阻力训练与无干预的比较(标准化均数差(SMD)=0.64;95%置信区间,0.22-1.07;p=0.003);阻力训练结合电刺激与无干预的比较(平均差异(MD)=14 Nm;95%置信区间,1-27;p=0.03);一套 PT 干预措施与无干预的比较(MD=4.8/50 分在下肢运动评分(LEMS);95%置信区间,1.9-7.7;p=0.01);机器人步态训练与地面步态训练的比较(MD=3.1/50 分在 LEMS 上;95%置信区间,1.3-5.0;p=0.0008)。
有证据表明,少数 PT 干预措施可以增加 SCI 直接影响的肌肉的自主力量。