Cevallos González Fabricio Marcelo, Dos Santos Araújo Erika Michele, Lorenzetti Simionato Maria Regina, Kfouri Siriani Luciana, Armas Vega Ana Del Carmen, Studart Medeiros Igor, Bona Matos Adriana
Inter Institutional PhD Program at School of Dentistry of University of São Paulo (USP), São Paulo, SP, Brazil.
School of Dentistry, Central University of Ecuador, Quito, Ecuador.
Prog Biomater. 2019 Mar;8(1):23-29. doi: 10.1007/s40204-019-0107-8. Epub 2019 Feb 6.
In vitro effect of 1% theobromine addition on the physical and chemical properties of conventional glass ionomer (GIC) cement was investigated. Conventional GIC (GIC-C) and 1% theobromine added to GIC (GIC-THEO) specimens were compared regarding the microhardness (n = 10), sorption (n = 5), solubility (n = 5), color change (n = 10), fluoride release in saliva (n = 10) and the amount of biofilm deposition (n = 20). Compared against conventional GIC, adding 1% theobromine increased microhardness (p < 0.05), while its sorption, solubility, color and fluoride release to saliva (p > 0.05) remained unchanged. On the other hand, Streptococcus mutans biofilm amount deposited on its surface decreased statistically when theobromine was added to GIC (p < 0.05). Based on the results, it could be concluded that 1% theobromine addition to GIC can be a good strategy as it keeps some of its properties and improves microhardness and biofilm deposits strengthening its role in the preventive approach of dentistry.
研究了添加1%可可碱对传统玻璃离子水门汀（GIC）物理和化学性能的体外影响。比较了传统GIC（GIC-C）和添加1%可可碱的GIC（GIC-THEO）试样的显微硬度（n = 10）、吸附性（n = 5）、溶解性（n = 5）、颜色变化（n = 10）、唾液中的氟释放量（n = 10）和生物膜沉积量（n = 20）。与传统GIC相比，添加1%可可碱可提高显微硬度（p < 0.05），而其吸附性、溶解性、颜色和唾液中的氟释放量（p > 0.05）保持不变。另一方面，当向GIC中添加可可碱时，其表面变形链球菌生物膜沉积量在统计学上减少（p < 0.05）。基于这些结果，可以得出结论，向GIC中添加1%可可碱可能是一种很好的策略，因为它保留了其一些性能，提高了显微硬度和生物膜沉积，增强了其在牙科预防方法中的作用。
