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活动性和稳定型甲状腺眼病患者脉络膜厚度的比较。

Comparison of choroidal thickness in patients with active and stable thyroid eye disease.

作者信息

Gul Adem, Basural Ekrem, Ozturk Hilal Eser

机构信息

Ophthalmology Department, Ondokuz Mayis University, Samsun, Turkey.

出版信息

Arq Bras Oftalmol. 2019 Mar-Apr;82(2):124-128. doi: 10.5935/0004-2749.20190019. Epub 2019 Jan 10.

DOI:10.5935/0004-2749.20190019
PMID:30726403
Abstract

PURPOSE

To compare the choroidal thickness in active and stable phases of thyroid eye disease.

METHODS

Forty-seven eyes of 47 patients with thyroid eye disease were prospectively studied. Patients were evaluated on the basis of their clinical activity scores, with scores 33 defined as active disease. Subfoveal, temporal macular, nasal macular, temporal peripapillary, and nasal peripapillary choroidal thickness measurements were performed with Cirrus enhanced depth imaging spectral-domain optical coherence tomography, and the results in the two groups were compared.

RESULTS

Twenty-four patients were int he active group, whereas 23 patients were in the stable group. Choroidal thickness was significantly higher in the subfoveal and temporal macular regions in the active group. Although the nasal macular and peripapillary values were also higher in the active group, the difference was insignificant.

CONCLUSIONS

Subfoveal choroidal thickness was significantly higher in patients with thyroid eye disease in the active phase than in those with stable phase disease.

摘要

目的

比较甲状腺眼病活动期和稳定期的脉络膜厚度。

方法

对47例甲状腺眼病患者的47只眼进行前瞻性研究。根据患者的临床活动评分进行评估,评分≥3分定义为疾病活动期。使用Cirrus增强深度成像光谱域光学相干断层扫描测量中心凹下、颞侧黄斑、鼻侧黄斑、颞侧视乳头周围和鼻侧视乳头周围的脉络膜厚度,并比较两组结果。

结果

活动组24例患者,稳定组23例患者。活动组中心凹下和颞侧黄斑区的脉络膜厚度显著更高。虽然活动组鼻侧黄斑和视乳头周围的值也较高,但差异不显著。

结论

甲状腺眼病活动期患者的中心凹下脉络膜厚度显著高于稳定期患者。

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