Niğde Ömer Halisdemir Training and Research Hospital, Clinic of Ophthalmology, Niğde, Turkey.
Ankara University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey.
Turk J Ophthalmol. 2020 Aug 26;50(4):221-227. doi: 10.4274/tjo.galenos.2020.97415.
To evaluate the effect of proptosis on choroidal thickness in patients with Graves' ophthalmopathy.
Twenty-five eyes of 25 Graves' patients with proptosis, 25 eyes of 25 Graves' patients without proptosis, and 25 eyes of 25 healthy individuals were included in this prospective study. The subfoveal choroidal thickness and choroidal thicknesses at 6 points from the fovea at 500 μm intervals were measured by Cirrus HD-OCT. All measurements were compared among the proptosis, non-proptosis, and control groups and the active, inactive, and control groups.
The mean subfoveal choroidal thickness in the proptosis group was 289.7±68.5 μm, 322.5±55.8 μm in the non-proptosis group, and 316.1±63.0 μm in the control group. The mean nasal choroidal thickness was 260.5±63.5 μm in the proptosis group, 293.9±57.9 μm in the non-proptosis group, and 279.5±63.1 μm in the control group. The mean temporal choroidal thickness was 261.8±60.9 μm in the proptosis group, 289.0±51.8 μm in the non-proptosis group, and 287.8±56.2 μm in the control group. Mean choroidal thickness was 264.7±58.5 μm in the proptosis group, 296.2±47.5 μm in the non-proptosis group, and 288.3±55.1 μm in the control group. There were no statistically significant differences among the groups with respect to choroidal thickness measurements (p>0.05).
No significant difference in choroidal thickness was detected between Graves' patients with and without proptosis and the controls. There was no effect of clinical activation on choroidal thickness.
评估Graves 眼病患者眼球突出对脉络膜厚度的影响。
本前瞻性研究纳入了 25 例Graves 病伴眼球突出患者的 25 只眼、25 例Graves 病无眼球突出患者的 25 只眼和 25 例健康对照者的 25 只眼。使用 Cirrus HD-OCT 测量黄斑中心凹下脉络膜厚度和距黄斑中心凹 500μm 处每隔 500μm 的 6 个点的脉络膜厚度。比较眼球突出组、无眼球突出组和对照组以及活动组、非活动组和对照组之间的所有测量值。
眼球突出组的平均黄斑中心凹下脉络膜厚度为 289.7±68.5μm，无眼球突出组为 322.5±55.8μm，对照组为 316.1±63.0μm。眼球突出组鼻侧脉络膜厚度的平均值为 260.5±63.5μm，无眼球突出组为 293.9±57.9μm，对照组为 279.5±63.1μm。眼球突出组颞侧脉络膜厚度的平均值为 261.8±60.9μm，无眼球突出组为 289.0±51.8μm，对照组为 287.8±56.2μm。眼球突出组平均脉络膜厚度为 264.7±58.5μm，无眼球突出组为 296.2±47.5μm，对照组为 288.3±55.1μm。各组间脉络膜厚度测量值无统计学差异（p＞0.05）。
Graves 病伴眼球突出与无眼球突出患者之间以及与对照组之间的脉络膜厚度无显著差异。临床活动状态对脉络膜厚度无影响。
