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直肠癌切除术后因渗漏形成的吻合口窦:在窦完全消退之前,我们应该等待造口关闭吗?

Anastomotic Sinus That Developed From Leakage After a Rectal Cancer Resection: Should We Wait for Closure of the Stoma Until the Complete Resolution of the Sinus?

作者信息

Chung Chris Tae-Young, Baek Se-Jin, Kwak Jung-Myun, Kim Jin, Kim Seon-Hahn

机构信息

Department of Surgery, Korea University College of Medicine, Seoul, Korea.

出版信息

Ann Coloproctol. 2019 Feb;35(1):30-35. doi: 10.3393/ac.2018.08.13. Epub 2019 Jan 25.

DOI:10.3393/ac.2018.08.13
PMID:30727707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6425247/
Abstract

PURPOSE

The aims of this study were to identify the clinical characteristics of an anastomotic sinus and to assess the validity of delaying stoma closure in patients until the complete resolution of an anastomotic sinus.

METHODS

The subject patients are those who had undergone a resection of rectal cancer from 2011 to 2017, who had a diversion ileostomy protectively or therapeutically and who developed a sinus as a sequelae of anastomotic leakage. The primary outcomes that were measured were the incidence, management and outcomes of an anastomotic sinus.

RESULTS

Of the 876 patients who had undergone a low anterior resection, 14 (1.6%) were found to have had an anastomotic sinus on sigmoidoscopy or a gastrografin enema before their ileostomy closure. In the 14 patients with a sinus, 7 underwent ileostomy closure as scheduled, with a mean closure time of 4.1 months. The remaining 7 patients underwent ileostomy repair, but it was delayed until after the follow-up for the widening of the sinus opening by using digital dilation, with a mean closure time of 6.9 months. Four of those remaining seven patients underwent stoma closure even though their sinus condition had not yet been completely resolved. No pelvic septic complications occurred after closure in any of the 14 patients with an anastomotic sinus, but 2 of the 14 needed a rediversion due to a severe anastomotic stricture.

CONCLUSION

Patients with an anastomotic sinus who had been carefully selected underwent successful ileostomy closure without delay.

摘要

目的

本研究旨在确定吻合口窦的临床特征,并评估在吻合口窦完全愈合之前延迟关闭造口对患者的有效性。

方法

研究对象为2011年至2017年接受直肠癌切除术、接受过预防性或治疗性回肠造口转流术且因吻合口漏出现吻合口窦后遗症的患者。测量的主要结局指标为吻合口窦的发生率、处理方式及结局。

结果

在876例行低位前切除术的患者中,14例(1.6%)在回肠造口关闭前经乙状结肠镜检查或泛影葡胺灌肠发现有吻合口窦。在这14例有窦的患者中,7例按计划关闭回肠造口,平均关闭时间为4.1个月。其余7例患者接受回肠造口修复,但延迟至通过手指扩张对窦口增宽进行随访之后,平均关闭时间为6.9个月。其余7例患者中有4例即使窦的情况尚未完全解决也进行了造口关闭。14例吻合口窦患者关闭造口后均未发生盆腔感染并发症,但14例中有2例因严重吻合口狭窄需要再次转流。

结论

经过精心挑选的吻合口窦患者成功且及时地关闭了回肠造口。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b15f/6425247/d55e5c371721/ac-2018-08-13f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b15f/6425247/ae7dcddc13f8/ac-2018-08-13f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b15f/6425247/58027cf2304e/ac-2018-08-13f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b15f/6425247/d55e5c371721/ac-2018-08-13f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b15f/6425247/ae7dcddc13f8/ac-2018-08-13f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b15f/6425247/58027cf2304e/ac-2018-08-13f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b15f/6425247/d55e5c371721/ac-2018-08-13f3.jpg

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引用本文的文献

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本文引用的文献

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The management of anastomotic pouch sinus after IPAA.回肠贮袋肛管吻合术后吻合口窦道的处理。
Dis Colon Rectum. 2012 May;55(5):541-8. doi: 10.1097/DCR.0b013e318244087c.
2
Factors associated with ileoanal pouch failure in patients developing early or late pouch-related fistula.与早期或晚期 pouch 相关瘘患者发生 ileoanal 袋失败相关的因素。
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The persisting presacral sinus after anastomotic leakage following anterior resection or restorative proctocolectomy.
直肠前切除或直肠结肠吻合术后吻合口漏致持续性骶前窦。
Colorectal Dis. 2011 Jan;13(1):26-9. doi: 10.1111/j.1463-1318.2010.02377.x.
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Chronic anastomotic sinus after low anterior resection: when can the defunctioning stoma be reversed?低位前切除术后慢性吻合口窦道:何时可反转预防性造口?
Colorectal Dis. 2011 Jun;13(6):644-9. doi: 10.1111/j.1463-1318.2010.02245.x. Epub 2010 Feb 20.
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Sepsis is a major predictor of failure after ileal pouch-anal anastomosis.脓毒症是回肠贮袋肛管吻合术后失败的主要预测因素。
Dis Colon Rectum. 2009 Dec;52(12):1975-81. doi: 10.1007/DCR.0b013e3181beb3f0.
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Endo-sponge assisted treatment of anastomotic leakage following colorectal surgery.内镜海绵辅助治疗结直肠手术后吻合口漏
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Anastomotic sinuses after ileoanal pouch construction: incidence, management, and outcome.回肠肛管吻合袋术后吻合窦:发生率、处理及结果
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The Dutch multicenter experience of the endo-sponge treatment for anastomotic leakage after colorectal surgery.荷兰关于结直肠手术后吻合口漏的内支架治疗的多中心经验。
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Persistent perineal sinus after ileoanal pouch excision in inflammatory bowel diseases: incidence, risk factors, and clinical course.炎症性肠病患者回肠储袋肛管吻合术后持续性会阴窦道:发病率、危险因素及临床病程
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