Howlader Debraj, Singh Vibha, Mohammad Shadab, Gupta Seema, Pal U S, Pal Mahesh
1Department of Oral and Maxillofacial Surgery, Faculty of Dental Sciences, King George's Medical University, Lucknow, India.
2Department of Radiation Oncology, King George's Medical University, Lucknow, India.
J Maxillofac Oral Surg. 2019 Mar;18(1):73-79. doi: 10.1007/s12663-017-1077-9. Epub 2018 Jan 11.
Oral cancer is a major health problem in India, and in certain parts, it represents more than 50% of all cancers. Since almost all of these patients receive chemo-radiotherapy with or without surgery for treatment, a vast majority of them also develop oral mucositis, a debilitating adverse effect of chemo-radiation. There have been various reports in the literature regarding the beneficial role of honey in the management of oral mucositis. The objective of this study was to investigate whether the application of honey in mucositis confers any significant improvement in lesions of mucositis and more specifically whether application of honey brings about any improvement in the quality of life of patients suffering from chemo-radiation-induced oral mucositis. If found to be beneficial, honey could provide a simple, elegant and cost-effective solution to a troublesome health problem, thus benefiting a large number of patients.
口腔癌是印度的一个主要健康问题，在某些地区，它占所有癌症的比例超过50%。由于几乎所有这些患者都接受了有或没有手术的放化疗，他们中的绝大多数还会出现口腔黏膜炎，这是放化疗的一种使人衰弱的副作用。关于蜂蜜在口腔黏膜炎管理中的有益作用，文献中有各种报道。本研究的目的是调查在黏膜炎中应用蜂蜜是否能显著改善黏膜炎病变，更具体地说，蜂蜜的应用是否能改善放化疗引起的口腔黏膜炎患者的生活质量。如果发现有益，蜂蜜可以为一个棘手的健康问题提供一个简单、优雅且具有成本效益的解决方案，从而使大量患者受益。
