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评估正丁基-2-氰基丙烯酸酯胶水(TRU SEAL)在口腔颌面部裂伤和手术切口闭合中的疗效和有效性。

To Evaluate the Efficacy and Effectiveness of N-butyl-2-cyanoacrylate glue (TRU SEAL) in Closure of Oral and Maxillofacial Laceration and Surgical Incisions.

作者信息

Singh Praveen Kumar, Degala Saikrishna, Shetty Sujeeth, Rai Vijay Singh, Das Asutosh

机构信息

Dr Praveen's Maxillofacial & Implant Centre, Gorakhpur, UP India.

2Department of Oral & Maxillofacial Surgery, JSS Dental College & Hospital, Mysuru, 570015 India.

出版信息

J Maxillofac Oral Surg. 2019 Mar;18(1):131-138. doi: 10.1007/s12663-018-1111-6. Epub 2018 Apr 21.

DOI:10.1007/s12663-018-1111-6
PMID:30728704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6328818/
Abstract

INTRODUCTION

Effective wound closure is critical for minimizing wound complications and preventing wound dehiscence. The various wound closure techniques include staples, traditional nylon and skin sutures, subcuticular sutures, and skin adhesives. Currently topical skin adhesives are frequently being used. It offers countless advantages: short application time, easy execution as well as possessing hemostatic character. N-butyl-2-cyanoacrylate is bacteriostatic and biodegradable and exhibits suitable tensile strength.

MATERIALS AND METHODS

Under nasoendotracheal intubation, the reduction in fracture and plating was done. In 80% of the patients, subcutaneous sutures were placed. Skin closure was done with N-butyl-2-cyanoacrylate glue.

RESULTS

In this study, REEDA scale was used to assess healing. Redness, edema, and ecchymosis were seen in all 10 patients, which subsided by the second week postoperatively. None of the patients had discharge from surgical site on the first postoperative day but was noted in two patients the first week postoperatively. There was evidence of wound gaping in one patient on the first postoperative day and two patients at end of the first week postoperatively. Stony Brook Scar Evaluation was used to evaluate postoperative cosmesis. No significant cosmetic impairment was found in all patients at the end of the study.

CONCLUSION

The study reflects qualitative assessment of cyanoacrylates which is simple to use and proper application which resulted in uniform and everted closure of wound. It is cost-efficient as compared to other wound closure materials.

摘要

引言

有效的伤口闭合对于将伤口并发症降至最低并防止伤口裂开至关重要。各种伤口闭合技术包括吻合钉、传统尼龙线和皮肤缝线、皮下缝线以及皮肤粘合剂。目前,局部皮肤粘合剂的使用频率很高。它具有无数优点:应用时间短、操作简便且具有止血特性。正丁基-2-氰基丙烯酸酯具有抑菌和可生物降解的特性,并具有合适的拉伸强度。

材料与方法

在鼻气管插管下进行骨折复位和钢板固定。80%的患者放置了皮下缝线。使用正丁基-2-氰基丙烯酸酯胶水进行皮肤闭合。

结果

在本研究中,使用REEDA量表评估愈合情况。所有10例患者均出现发红、水肿和瘀斑,在术后第二周消退。所有患者术后第一天手术部位均无渗液,但术后第一周有2例患者出现渗液。有1例患者术后第一天出现伤口裂开,2例患者术后第一周结束时出现伤口裂开。使用石溪瘢痕评估法评估术后美容效果。在研究结束时,所有患者均未发现明显的美容缺陷。

结论

该研究反映了氰基丙烯酸酯的定性评估,其使用简单且应用得当,可实现伤口的均匀外翻闭合。与其他伤口闭合材料相比,它具有成本效益。

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