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氰基丙烯酸正丁酯组织粘合剂与Ethilon尼龙缝线用于口腔外颌面切口的比较:一项随机前瞻性研究。

Comparison between N-butyl cyanoacrylate tissue adhesive and Ethilon nylon sutures in extraoral maxillofacial incisions: A randomized prospective study.

作者信息

Sahu Sudipto, Mishra Sobhan, Lenka Sthitaprajna, Banerjee Rajarshi, Pachisia Sandeep, Ghosh Sucharu

机构信息

Dept of Oral and Maxillofacial Surgery, Haldia Institute of Dental Sciences and Research, West Bengal University of Health Sciences, Haldia, West Bengal, India.

Dept of Oral and Maxillofacial Surgery, Institute of Dental Sciences, Siksha 'O' Anusandhan University, Bhubaneswar, Odisha, India.

出版信息

J Oral Biol Craniofac Res. 2019 Jul-Sep;9(3):173-178. doi: 10.1016/j.jobcr.2019.04.002. Epub 2019 Apr 16.

Abstract

OBJECTIVES

Wound closure is a part of any surgical procedure. Wound care and healing process are concepts, which are usually reliant upon sutures. The suture and non-suture repair of the tissues has been a major concern to surgeons for over four thousand years. The objective of this study is to compare the rates of infection, wound dehiscence, necrosis and time required by N-butyl cyanoacrylate tissue adhesive and nylon sutures in extraoral maxillofacial wound closer.

MATERIALS AND METHODS

24 patients requiring external wound closing were included in this study. Patients were divided in two groups, in one group wound closer was done by N-butyl cyanoacrylate tissue adhesive and by conventional nylon suture in the other group. The software STATA of StataCorp was used in statistical analysis if this study.

RESULTS

Wound infection, dehiscence, necrosis of tissue edges, time taken for closure was much less in case of tissue adhesive than conventional sutures.

CONCLUSION

Advantages of tissue adhesives over conventional wound closure techniques include easy to use, excellent bacteriostatic property, decreased repair time, elimination of recall visits and comparable short and long-term cosmetic outcome. Though tissue adhesives have many advantages over conventional wound closure techniques, they can be used as an alternative to sutures only in superficial small and tension free skin incisions or lacerations.

摘要

目的

伤口闭合是任何外科手术的一部分。伤口护理和愈合过程是通常依赖缝线的概念。组织的缝合和非缝合修复四千多年来一直是外科医生主要关注的问题。本研究的目的是比较在口腔外颌面伤口闭合中,氰基丙烯酸正丁酯组织粘合剂和尼龙缝线的感染率、伤口裂开率、坏死率以及所需时间。

材料与方法

本研究纳入了24例需要进行外部伤口闭合的患者。患者被分为两组,一组使用氰基丙烯酸正丁酯组织粘合剂进行伤口闭合,另一组使用传统尼龙缝线。本研究的统计分析使用了StataCorp公司的STATA软件。

结果

与传统缝线相比,使用组织粘合剂时伤口感染、裂开、组织边缘坏死以及闭合所需时间要少得多。

结论

组织粘合剂相对于传统伤口闭合技术的优点包括使用方便、出色的抑菌性能、减少修复时间、无需复诊以及短期和长期美容效果相当。尽管组织粘合剂相对于传统伤口闭合技术有许多优点,但它们仅可用于浅表、小且无张力的皮肤切口或裂伤,作为缝线的替代方法。

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