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使用蓝色胶水进行口腔黏膜伤口闭合——一项前瞻性临床研究。

Attached Oral Mucosal Wound Closure using Blue Glue - A Prospective Clinical Study.

作者信息

Narsingyani Roma Gopaldas, Patel Shital Mayank, Sood Ramita Atul, Bhimani Kruna K, Makwana Sanjaykumar V, Savani Rajan R

机构信息

Department of Oral and Maxillofacial Surgery, AMC Dental College and Hospital, Gujarat University, Ahmedabad, Gujarat, India.

出版信息

Ann Maxillofac Surg. 2023 Jan-Jun;13(1):31-36. doi: 10.4103/ams.ams_2_23. Epub 2023 Jul 28.

Abstract

INTRODUCTION

Traditionally, sutures have been widely used to close intraoral wounds. Various alternatives have been developed amongst which newer tissue adhesives such as N-butyl-2-cyanoacrylate having accepted clinical properties are gaining popularity. The primary purpose of the present study is to evaluate the efficacy of N-butyl-2-cyanoacrylate for intraoral attached mucosal wound closure following alveoloplasty.

MATERIALS AND METHODS

In this prospective split-mouth study, 25 patients requiring alveoloplasty in either maxillary or mandibular arch bilaterally with a total of 50 sites were divided into two equal groups, namely silk suture (Group 1) and cyanoacrylate (Group 2). Each patient was evaluated on the first, third, seventh, 14 and 21 post-operative days. Parameters evaluated were time taken to close incision and to achieve haemostasis, pain, oedema, post-operative wound healing, patient discomfort and possible complications.

RESULTS

Time taken to close incision, time taken to achieve haemostasis, post-operative pain and oedema were found to be less in Group 2. Wound healing too was found to be better in Group 2. There was one case of adhesive peel off on the first post-operative day which was managed by reapplying the tissue adhesive. The incidence of wound dehiscence and wound infection was observed more in Group 1 on the third post-operative day. Suture breakage (16%) and adhesive dislodgement (8%) were reported on the seventh post-operative day.

DISCUSSION

The use of cyanoacrylates' inherent benefits, such as improved wound seal off in attached mucosa, quick polymerisation and bacteriostatic characteristics can be beneficial when performing minor oral surgical procedures on elderly, young and mentally challenged patients.

摘要

引言

传统上,缝线已被广泛用于闭合口腔内伤口。人们开发了各种替代方法,其中具有公认临床特性的新型组织粘合剂,如N-丁基-2-氰基丙烯酸酯越来越受欢迎。本研究的主要目的是评估N-丁基-2-氰基丙烯酸酯在牙槽成形术后用于口腔内附着黏膜伤口闭合的疗效。

材料与方法

在这项前瞻性双侧口内对照研究中,25例双侧上颌或下颌弓需要进行牙槽成形术的患者,共50个手术部位,被分为两组,即丝线缝合组(第1组)和氰基丙烯酸酯组(第2组)。在术后第1、3、7、14和21天对每位患者进行评估。评估的参数包括切口闭合时间、止血时间、疼痛、水肿、术后伤口愈合情况、患者不适以及可能的并发症。

结果

发现第2组的切口闭合时间、止血时间、术后疼痛和水肿较轻。第2组的伤口愈合情况也较好。术后第1天有1例粘合剂脱落,通过重新涂抹组织粘合剂进行处理。术后第3天,第1组伤口裂开和伤口感染的发生率更高。术后第7天报告有缝线断裂(16%)和粘合剂移位(8%)。

讨论

在对老年、年轻和智力障碍患者进行小型口腔外科手术时,使用氰基丙烯酸酯的固有优点,如改善附着黏膜的伤口封闭、快速聚合和抑菌特性可能是有益的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d72/10499272/a064aaee1f0e/AMS-13-31-g001.jpg

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