Le Tourneau A, Caulet S, Audouin J, Diebold J
Service Central "Jacques Delarue" d'Anatomie et de Cytologie Pathologiques, Paris.
Ann Med Interne (Paris). 1988;139(7):464-8.
In the last few years advances in immunopathology have demonstrated the T cell origins of some malignant lymphoma (ML). Histopathological criteria have been suggested for classifying several varieties of T cell ML. Peripheral T cell ML are the result of proliferation of T cell lymphocytes with markers which distinguish between the enhancing-inducer and suppressor-cytotoxic forms. The diagnosis is made from the appearances of the cell, the presence of vascular hyperplasia and associated lesions. The numbers of small, medium and large cells and clinical follow-up of these tumors have provided a means of distinguishing between low and highly malignant tumors. Some peripheral T cell ML have associated lesions due to the secretion of lymphokines which give characteristic histopathological appearances (lympho-epithelioid T cell ML, AIL type T cell ML). The authors discuss the respective places of each variety of peripheral T cell ML in Lennert and Suchi's classification which is an extension of that proposed by Kiel, and their prognostic signification.
在过去几年中，免疫病理学的进展已证实某些恶性淋巴瘤（ML）起源于T细胞。已提出组织病理学标准用于对几种T细胞ML进行分类。外周T细胞ML是具有区分增强诱导型和抑制细胞毒性型标志物的T淋巴细胞增殖的结果。诊断依据细胞外观、血管增生的存在及相关病变做出。这些肿瘤中小、中、大细胞的数量以及临床随访提供了区分低恶性和高恶性肿瘤的方法。一些外周T细胞ML因淋巴因子分泌而伴有特征性组织病理学表现的病变（淋巴上皮样T细胞ML，AIL型T细胞ML）。作者讨论了外周T细胞ML各类型在Lennert和Suchi分类（这是对Kiel提出的分类的扩展）中的各自位置及其预后意义。
