Ragab Rasha Adel, Lattif Amr Ezzat Abd El, Dokky Norhan Abd El Wahab El
J Clin Pediatr Dent. 2019;43(2):78-85. doi: 10.17796/1053-4625-43.2.2. Epub 2019 Feb 7.
This study was conducted to evaluate the effect of platelet rich fibrin (PRF) during revitalization of necrotic immature permanent anterior teeth after 6 months and 1 year follow up period. The following treatment protocols; Group A: revitalization using blood clot scaffold only, and Group B: revitalization using blood clot and PRF.
twenty-two patients (7-12 years old) suffering from immature necrotic permanent maxillary central incisors were randomly selected and randomly allocated into 2 groups. Clinical examinations were performed to detect any pain or swelling during the follow up period. Standardized radiographs were digitally evaluated for changes in root length, periapical radiolucency size, presence of apical or cervical calcific bridges.
After a follow-up period of 12 months, most of the cases showed radiographic evidence of periapical healing and showed calcific bridges either cervical and/or apical. No significant differences were shown between both groups.
The revitalization procedures succeeded to show continued development of roots in teeth with necrotic pulps. The use of PRF was not essential for repair but it helped during the procedures.
本研究旨在评估富血小板纤维蛋白（PRF）在坏死未成熟恒前牙再生活化6个月和1年随访期后的效果。采用以下治疗方案：A组：仅使用血凝块支架进行再生活化；B组：使用血凝块和PRF进行再生活化。
随机选取22例（7 - 12岁）患有未成熟坏死恒上颌中切牙的患者，并随机分为2组。在随访期间进行临床检查，以检测是否有疼痛或肿胀。对标准化X线片进行数字化评估，以观察牙根长度、根尖周透射区大小、根尖或颈部钙化桥的情况。
随访12个月后，大多数病例显示根尖周愈合的影像学证据，并显示有颈部和/或根尖钙化桥。两组之间未显示出显著差异。
再生活化程序成功地显示了牙髓坏死牙齿牙根的持续发育。PRF的使用对修复并非必不可少，但在操作过程中有所帮助。
