Tucker J A
Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710.
J Electron Microsc Tech. 1988 Jan;8(1):137-58. doi: 10.1002/jemt.1060080110.
Malignancies frequently arise in patients infected with human immunodeficiency virus (HIV), including those patients classified as having the acquired immunodeficiency syndrome (AIDS). Currently, Kaposi's sarcoma and certain types of lymphoma are considered to develop as a result of HIV infection, and other cancers have also been reported in these patients. For the most part, ultrastructural study of HIV-associated malignancies has been limited to Kaposi's sarcoma; the ultrastructural features of the epidemic form of this disease are generally the same as those of the classical form. The occurrence of these cancers in HIV-infected individuals appears to be related to the immunodeficiency caused by this virus, but the basic etiologic mechanisms remain unknown. In general, only palliative treatments are presently available for HIV-associated malignancies.
恶性肿瘤经常出现在感染人类免疫缺陷病毒（HIV）的患者中，包括那些被归类为患有获得性免疫缺陷综合征（AIDS）的患者。目前，卡波西肉瘤和某些类型的淋巴瘤被认为是由HIV感染引起的，这些患者中也报告了其他癌症。在很大程度上，对HIV相关恶性肿瘤的超微结构研究仅限于卡波西肉瘤；这种疾病流行形式的超微结构特征通常与经典形式相同。这些癌症在HIV感染个体中的发生似乎与这种病毒引起的免疫缺陷有关，但基本病因机制仍然未知。一般来说，目前对于HIV相关恶性肿瘤只有姑息治疗方法。
