Polk H C
Department of Surgery, University of Louisville School of Medicine, Kentucky 40292.
Jpn J Surg. 1988 Nov;18(6):609-14. doi: 10.1007/BF02471519.
A sequence of studies over more than two decades has identified a variety of host defense abnormalities that may contribute to clinical infection in high risk and/or badly injured patients. Clearly, animal studies set the stage for our clinical applications and suggest that a variety of so-called non-specific host defense stimulants may indeed correct many of these abnormalities and promote the ultimate control of surgical infections.
二十多年来的一系列研究已经确定了多种宿主防御异常情况，这些异常可能导致高危和/或重伤患者发生临床感染。显然，动物研究为我们的临床应用奠定了基础，并表明各种所谓的非特异性宿主防御刺激剂确实可以纠正许多此类异常情况，并促进手术感染的最终控制。
