Morotomi Takahiko, Washio Ayako, Kitamura Chiaki
Division of Endodontics and Restorative Dentistry, Department of Science of Oral Functions, Kyushu Dental University, 2-6-1 Manazuru, Kokurakita-ku, Kitakyushu 803-8580, Japan.
Jpn Dent Sci Rev. 2019 Nov;55(1):5-11. doi: 10.1016/j.jdsr.2018.09.001. Epub 2018 Sep 29.
Dental pulp is a connective tissue and has functions that include initiative, formative, protective, nutritive, and reparative activities. However, it has relatively low compliance, because it is enclosed in hard tissue. Its low compliance against damage, such as dental caries, results in the frequent removal of dental pulp during endodontic therapy. Loss of dental pulp frequently leads to fragility of the tooth, and eventually, a deterioration in the patient's quality of life. With the development of biomaterials such as bioceramics and advances in pulp biology such as the identification of dental pulp stem cells, novel ideas for the preservation of dental pulp, the regenerative therapy of dental pulp, and new biomaterials for direct pulp capping have now been proposed. Therapies for dental pulp are classified into three categories; direct pulp capping, vital pulp amputation, and treatment for non-vital teeth. In this review, we discuss current and future treatment options in these therapies.
牙髓是一种结缔组织，具有包括起始、形成、保护、营养和修复活动等功能。然而，由于它被包在硬组织中，其顺应性相对较低。它对诸如龋齿等损伤的低顺应性导致在牙髓治疗期间经常需要去除牙髓。牙髓丧失常常导致牙齿脆弱，最终使患者的生活质量下降。随着生物陶瓷等生物材料的发展以及牙髓生物学的进步，如牙髓干细胞的鉴定，现在已经提出了保存牙髓的新想法、牙髓再生疗法以及用于直接盖髓的新型生物材料。牙髓治疗方法分为三类：直接盖髓、活髓切断术和对无活力牙的治疗。在这篇综述中，我们讨论这些治疗方法中的当前和未来治疗选择。
