Imaeda Hiroyuki, Hibi Toshifumi
Department of Gastroenterology, Saitama Medical University, Saitama, Japan.
Center for Advanced IBD Research and Treatment, Kitasato University Kitasato Institute Hospital, Tokyo, Japan.
Inflamm Intest Dis. 2018 Dec;3(2):61-68. doi: 10.1159/000492178. Epub 2018 Aug 7.
Colonic diverticulosis is prevalent and increasing not only in Western but also in Asian countries. Diverticulosis can be complicated by diverticulitis and diverticular bleeding. Diverticular disease is a burdensome digestive disease, because it is a major cause of hospital admissions and is associated with significant health-care costs.
The incidence of diverticulosis increases with age. Most cases of diverticulosis in Western countries involve the left side of the colon, while diverticulosis is predominantly present on the right side of the colon in Asian countries. The incidence of diverticulitis also increases with age. Diverticulitis is predominantly located on the left side of the colon in Western countries, while it is predominantly located on the right side of the colon in Asian countries. The overall complication rate is higher in left-sided than in right-sided diverticulitis. The incidence of diverticular bleeding also increases with age. The right colon is the source of diverticular bleeding in more than 50% of patients in Western countries. In Asian countries, age greater than 70 years and both-sided diverticulosis increase the bleeding risk.
In Western countries, diverticulosis and diverticulitis are predominantly located on the left side of the colon, whereas they are predominantly present on the right side of the colon in Asian countries. Diverticular bleeding is predominantly located on the right side in Western countries, and both-sided diverticulosis increases the risk of bleeding in Asian countries. Diverticular disease with complications requires admission and operation; moreover, it recurs frequently. Therefore, diverticular disease is associated with a significant economic burden in terms of health-care costs and resource utilization.
结肠憩室病不仅在西方国家，而且在亚洲国家都很普遍且呈上升趋势。憩室病可能并发憩室炎和憩室出血。憩室病是一种负担沉重的消化系统疾病，因为它是住院的主要原因，且与高昂的医疗费用相关。
憩室病的发病率随年龄增长而增加。西方国家的大多数憩室病病例累及结肠左侧，而在亚洲国家，憩室病主要出现在结肠右侧。憩室炎的发病率也随年龄增长而增加。在西方国家，憩室炎主要位于结肠左侧，而在亚洲国家，它主要位于结肠右侧。左侧憩室炎的总体并发症发生率高于右侧。憩室出血的发病率也随年龄增长而增加。在西方国家，超过50%的患者憩室出血源自右结肠。在亚洲国家，年龄大于70岁和双侧憩室病会增加出血风险。
在西方国家，憩室病和憩室炎主要位于结肠左侧，而在亚洲国家，它们主要出现在结肠右侧。在西方国家，憩室出血主要位于右侧，而在亚洲国家，双侧憩室病会增加出血风险。伴有并发症的憩室病需要住院和手术治疗；此外，它还经常复发。因此，憩室病在医疗费用和资源利用方面会带来巨大的经济负担。
