自组装磁性 DNA 水凝胶作为一种新型生物材料用于酶封装，可提高酶的活性和稳定性。
Self-assembly of a magnetic DNA hydrogel as a new biomaterial for enzyme encapsulation with enhanced activity and stability.
机构信息
Beijing Key Laboratory of Environmentally Harmful Chemical Analysis, College of Science, Beijing University of Chemical Technology, Beijing 100029, P. R. China.
出版信息
Chem Commun (Camb). 2019 Feb 21;55(17):2449-2452. doi: 10.1039/c8cc09717h.
PMID:30734040
Abstract
We provide a new strategy to construct a magnetic DNA hydrogel for enzyme encapsulation through a programmable one-pot self-assembly approach, which can be easily separated from the reaction medium. The encapsulated enzyme composites exhibited significantly improved enzymatic activity, stability, reusability and excellent selectivity for the detection of low concentrations of glucose.
摘要
我们提供了一种新的策略，通过可编程的一步自组装方法构建用于酶封装的磁性 DNA 水凝胶，该水凝胶可以很容易地从反应介质中分离出来。封装的酶复合材料表现出显著提高的酶活性、稳定性、可重复使用性和对低浓度葡萄糖检测的优异选择性。
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