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经尿道前列腺整块剜除术联合早期顶端松解术治疗良性前列腺增生。

'En Bloc' HoLEP with early apical release in men with benign prostatic hyperplasia.

机构信息

ICUA-Clínica CEMTRO, Av. Ventisquero de la Condesa 42, 28035, Madrid, Spain.

IRCCS Ospedale San Raffaele, Via Stamira d'Ancona 20, 20127, Milan, Italy.

出版信息

World J Urol. 2019 Nov;37(11):2451-2458. doi: 10.1007/s00345-019-02671-4. Epub 2019 Feb 8.

Abstract

PURPOSE

HoLEP represents an excellent treatment option for benign prostatic hyperplasia. Recently, 'en bloc' techniques resulting in improved visualization, shorter surgical times, and easier recognition of the dissection plane have been described. In this paper we describe the 'En bloc' HoLEP technique with early apical release.

MATERIALS AND METHODS

Between January 2015 and March 2017, 137 consecutive patients were subjected to this technique by a single surgeon. The following parameters were measured pre- and post-procedure: International Prostate Symptom Score (IPSS), maximum flow rate (Q), post-void residual urine (PVR) and PSA. Complications were recorded.

RESULTS

Mean (SD; range) age was 66 years (8.0; 51-84), mean PSA was 4.8 ng/ml (7.0; 0.3-70), mean prostate volume was 75.63 ml (42.1; 37-253), mean volume of prostatic tissue removed was 65.9 ml (35.8; 30-217). Mean surgical duration was 47.58 min (21.3; 15-120 min): enucleation 31.5 min (14.9; 5-80 min), morcellating 6.9 min (6.6; 1-60 min). Mean hospitalization duration was 1.2 days (range 1-3), mean catheterization time was 1.2 days (range 1-5). The rate of stress urinary incontinence (SUI) was 5.8, 1.5 and 0.7% at 1, 3, and 6 months post-operation, respectively. Compared to pre-operative values, IPSS, Q, and PVR showed significant improvements at 1, 3, 6, and 12 months following the operation (p < 0.05).

CONCLUSIONS

'En Bloc' HoLEP with early apical release is a safe technique that allows for easier recognition of the surgical plane and preserves the external sphincter's mucosa to provide low rates of post-operative stress incontinence and significant functional results.

摘要

目的

HoLEP 是治疗良性前列腺增生的一种极好的治疗选择。最近,描述了能够改善可视化、缩短手术时间和更容易识别解剖平面的“整块”技术。本文介绍了带有早期顶端释放的“整块”HoLEP 技术。

材料与方法

2015 年 1 月至 2017 年 3 月,由一位外科医生对 137 例连续患者进行了该技术。术前和术后测量以下参数:国际前列腺症状评分(IPSS)、最大流量率(Q)、残余尿后(PVR)和 PSA。记录并发症。

结果

平均(SD;范围)年龄为 66 岁(8.0;51-84),平均 PSA 为 4.8ng/ml(7.0;0.3-70),平均前列腺体积为 75.63ml(42.1;37-253),切除的前列腺组织平均体积为 65.9ml(35.8;30-217)。平均手术时间为 47.58 分钟(21.3;15-120 分钟):剥离 31.5 分钟(14.9;5-80 分钟),碎解 6.9 分钟(6.6;1-60 分钟)。平均住院时间为 1.2 天(范围 1-3),平均导管时间为 1.2 天(范围 1-5)。术后 1、3 和 6 个月,压力性尿失禁(SUI)的发生率分别为 5.8%、1.5%和 0.7%。与术前值相比,术后 1、3、6 和 12 个月时,IPSS、Q 和 PVR 均有显著改善(p<0.05)。

结论

带有早期顶端释放的“整块”HoLEP 是一种安全的技术,它可以更容易地识别手术平面,并保留外括约肌的粘膜,以提供较低的术后压力性尿失禁发生率和显著的功能结果。

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