单细胞显微镜下的人类精原干细胞研究。
Human Spermatogonial Stem Cells Scrutinized under the Single-Cell Magnifying Glass.
机构信息
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92093, USA.
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Diego, La Jolla, CA 92093, USA; Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
出版信息
Cell Stem Cell. 2019 Feb 7;24(2):201-203. doi: 10.1016/j.stem.2019.01.010.
Abstract
Spermatogonial stem cells (SSCs) are essential for adult spermatogenesis. Recently, Wang et al. (2018), Guo et al. (2018), and Hermann et al. (2018) used single-cell RNA sequencing to define and molecularly characterize human testicular cell populations, including spermatogonial subsets with characteristics of human SSCs.
摘要
精原干细胞（SSCs）对于成人精子发生至关重要。最近，Wang 等人（2018 年）、Guo 等人（2018 年）和 Hermann 等人（2018 年）使用单细胞 RNA 测序来定义和分子表征人类睾丸细胞群体，包括具有人类 SSCs 特征的精原细胞亚群。
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