Department of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei 11219, Taiwan.
Department of Aquatic Sport, University of Taipei, Taipei 11153, Taiwan.
Nutrients. 2019 Feb 7;11(2):353. doi: 10.3390/nu11020353.
A triathlon, which consists of swimming, bicycling, and running, is a high-intensity and long-term form of exercise that can cause injuries such as muscular damage, inflammation, oxidative stress, and energy imbalance. Probiotics are thought to play an important role in disease incidence, health promotion, and nutrient metabolism, but only a few studies have focused on physiological adaptations to exercise in sports science. Previous studies indicated that Lactobacillus supplementation could improve oxidative stress and inflammatory responses. We investigate the effects of Lactobacillus plantarum PS128 supplementation on triathletes for possible physiological adaptation. The triathletes were assigned to one of two groups with different exercise intensity stimulations with different time-points to investigate the effects of body compositions, inflammation, oxidative stress, performance, fatigue, and injury-related biochemical indices. L. plantarum PS128 supplementation, combined with training, can significantly alleviate oxidative stress (such as creatine kinase, Thioredoxin, and Myeloperoxidase indices) after a triathlon (p < 0.05). This effect is possibly regulated by a 6⁻13% decrease of indicated pro-inflammation (TNF-α, IL-6, and IL-8) cytokines (p < 0.05) and 55% increase of anti-inflammation (IL-10) cytokines (p < 0.05) after intensive exercise stimulation. In addition, L. plantarum PS128 can also substantially increase 24⁻69% of plasma-branched amino acids (p < 0.05) and elevate exercise performance, as compared to the placebo group (p < 0.05). In conclusion, L. plantarum PS128 may be a potential ergogenic aid for better training management, physiological adaptations to exercise, and health promotion.
一项由游泳、骑自行车和跑步组成的三项全能运动是一种高强度和长期的运动形式，可能会导致肌肉损伤、炎症、氧化应激和能量失衡等损伤。益生菌被认为在疾病发病、促进健康和营养代谢方面发挥着重要作用，但只有少数研究关注运动科学中对运动的生理适应。以前的研究表明，补充乳酸菌可以改善氧化应激和炎症反应。我们研究了植物乳杆菌 PS128 补充剂对三项全能运动员的影响，以寻找可能的生理适应。将三项全能运动员分为两组，两组的运动强度刺激不同，时间点也不同，以研究身体成分、炎症、氧化应激、表现、疲劳和与损伤相关的生化指标的影响。植物乳杆菌 PS128 补充剂与训练相结合，可以显著减轻三项全能运动后的氧化应激（如肌酸激酶、硫氧还蛋白和髓过氧化物酶指标）（p<0.05）。这种作用可能是通过降低 6-13%的炎症标志物（TNF-α、IL-6 和 IL-8）（p<0.05）和增加 55%的抗炎标志物（IL-10）（p<0.05）来调节的。此外，与安慰剂组相比，植物乳杆菌 PS128 还可以显著增加 24-69%的血浆支链氨基酸（p<0.05），提高运动表现（p<0.05）。总之，植物乳杆菌 PS128 可能是一种潜在的运动补剂，可以更好地进行训练管理、适应运动的生理变化和促进健康。
