Sapin M R, Bulanova G V
Arkh Anat Gistol Embriol. 1988 Dec;95(12):5-13.
The ellipsoids of the spleen are considered as one of the links of the immune (lymphoid) apparatus of the lymphoreticular organ. Anatomical peculiarities of interrelations between the wall of the terminal part of the arterial bed, capillary, ellipsoid macrophagal-lymphoid microenvironment and reticular stroma of the ellipsoids of the spleen are discussed. Certain ultrastructural and immune-histological differences in the structure of the endothelial lining and cells, forming the ellipsoid sheaths, demonstrate functional interconnection of these formations not only with regulation of blood stream in the spleen vascular bed, but with transport of the antigenic material and lymphocytes into the white pulp. However, the functional appointment, as well as using of terminology of these formations still remain to be cleared out. An analogy is made, concerning the function of the splenic ellipsoid sheaths and postcapillary venules of the lymph node. The formation of the structural mechanism of immune response to the antigen-antibody complexes are analyzed, using some examples of evolutionary development of the ellipsoid macrophagal-lymphoid sheaths in various animal species.
脾椭球体被视为淋巴网状器官免疫（淋巴）装置的连接环节之一。本文讨论了脾椭球体动脉床终末部分壁、毛细血管、椭球体巨噬细胞 - 淋巴细胞微环境与网状基质之间相互关系的解剖学特点。构成椭球体鞘的内皮衬里和细胞结构存在某些超微结构和免疫组织学差异，这表明这些结构不仅与脾血管床血流调节功能相关，还与抗原物质和淋巴细胞向白髓的转运功能相关。然而，这些结构的功能定位以及术语使用仍有待明确。文中对脾椭球体鞘与淋巴结毛细血管后微静脉的功能进行了类比。通过各种动物物种椭球体巨噬细胞 - 淋巴细胞鞘进化发育的一些例子，分析了对抗原 - 抗体复合物免疫反应结构机制的形成。
