Aneja Tripti, Chaturvedula Latha, Nair Pradeep Pankajakshan, Barathi Deepak, Keepanasseril Anish
Department of Obstetrics and Gynecology, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry, India.
Department of Neurology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
BMJ Case Rep. 2019 Feb 7;12(2):e227530. doi: 10.1136/bcr-2018-227530.
Wernicke's encephalopathy (WE) is an uncommon neurological complication in pregnancies complicated with hyperemesis due to thiamine deficiency. In women with hyperemesis, inadvertent glucose administration prior to thiamine supplementation triggers the development of neurological manifestations. Delay in the diagnosis can lead to maternal morbidity, and in one-third of cases may lead to persistence of some neurological deficit. With early recognition and thiamine supplementation, complete recovery is reported. We report a case of WE complicating a case of triplet pregnancy with hyperemesis gravidarum, which highlights the importance of early recognition and treatment, resulting in complete recovery as in the index case.
韦尼克脑病（WE）是妊娠合并妊娠剧吐时因硫胺素缺乏引起的一种罕见神经并发症。在妊娠剧吐的女性中，补充硫胺素之前不慎输注葡萄糖会引发神经症状。诊断延误可导致母体发病，三分之一的病例可能遗留一些神经功能缺损。据报道，早期识别并补充硫胺素可实现完全康复。我们报告一例三胎妊娠合并妊娠剧吐并发韦尼克脑病的病例，该病例突出了早期识别和治疗的重要性，最终如同索引病例一样实现了完全康复。
