Cengiz Huseyin, Kaya Cihan, Suzen Caypinar Sema, Alay Ismail
a Department of Obstetrics and Gynecology , University of Health Sciences Bakirkoy Dr. Sadi Konuk Teaching and Research Hospital , Istanbul , Turkey.
b Department of Obstetrics and Gynecology , Bahcelievler State Hospital , Istanbul , Turkey.
J Obstet Gynaecol. 2019 May;39(4):529-533. doi: 10.1080/01443615.2018.1534812. Epub 2019 Feb 11.
The most common symptoms during menopausal transition and menopause are vasomotor symptoms. We aimed to investigate the relationship between menopausal symptoms and metabolic syndrome (MetS) in postmenopausal women. Two hundred and fifty-four and 317 postmenopausal women were in the MetS and non-MetS groups, respectively. The total menopause rating scale and psychological subscale scores were higher in the MetS group than the non-MetS group, and the differences were significant (p < .05). A positive correlation was found between the abdominal circumferences, systolic-diastolic blood pressures, triglycerides and total MRS scores. However, a significant positive correlation was found between the abdominal circumference and total urogenital scores (p = .008). Impact statement What is already known on this subject? MetS and its dominant component (abdominal obesity) significantly increase the prevalence and severity of menopausal symptoms. Data regarding the relationship between metabolic syndrome (MetS) and vasomotor symptoms remain limited. What do the results of this study add? We showed that sleeping problems, depressive symptoms and bladder problems were more frequently encountered in the MetS group than in the non-MetS group (p<0.05). What are the implications of these findings for clinical practice and/or further research? There is a need for more randomised controlled studies to demonstrate the relationship between MetS and the severity of menopausal symptoms.
绝经过渡和绝经期间最常见的症状是血管舒缩症状。我们旨在研究绝经后女性绝经症状与代谢综合征(MetS)之间的关系。MetS组和非MetS组分别有254名和317名绝经后女性。MetS组的总绝经评分量表和心理子量表得分高于非MetS组,差异有统计学意义(p < 0.05)。腹围、收缩压-舒张压、甘油三酯与总MRS评分之间呈正相关。然而,腹围与总泌尿生殖系统评分之间存在显著正相关(p = 0.008)。影响声明关于该主题已知的信息有哪些?MetS及其主要成分(腹型肥胖)显著增加绝经症状的患病率和严重程度。关于代谢综合征(MetS)与血管舒缩症状之间关系的数据仍然有限。本研究的结果增加了哪些内容?我们表明,MetS组比非MetS组更频繁地出现睡眠问题、抑郁症状和膀胱问题(p<0.05)。这些发现对临床实践和/或进一步研究有何意义?需要更多的随机对照研究来证明MetS与绝经症状严重程度之间的关系。