Department of Surgery, Faculty of Medicine and Dentistry, 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, Edmonton, Canada.
Department of Surgery, Faculty of Medicine and Dentistry, 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, Edmonton, Canada.
Surg Obes Relat Dis. 2019 Mar;15(3):431-440. doi: 10.1016/j.soard.2018.12.035. Epub 2019 Jan 11.
Complications arising from laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are not insignificant and can necessitate additional invasive interventions or reoperations.
In this study, we identify early complications that result in nonoperative and operative interventions after LSG and LRYGB, the timeframe within which to expect them, and factors that influence the likelihood of their occurrence.
Multi-institutional database from across North America.
Data for this study were obtained from Metabolic and Bariatric Accreditation and Quality Improvement Program participant use files for 2015 and 2016. Statistical analysis was performed using STATA 15. Univariate analysis using Χ for categoric data and independent t test for continuous data was performed to determine between group differences. Multivariable logistic regression analysis was used to identify predictors of operative and nonoperative reinterventions.
In 2015 and 2016, 243,747 underwent LRYGB or LSG, of which 3013 (1.24%) required a second operative procedure and 1536 (0.63%) required an invasive but nonoperative intervention. Complications occurred in 5.48% of LRYGB patients and 2.28% of LSG patients, the most common of which was bleeding. LSG was associated with far fewer nonoperative and operative interventions (.85% versus 2.2%, respectively) than LRYGB (.67% versus 2.5%). Renal insufficiency, including dialysis dependency, was an important predictor of reoperations among bariatric surgery patients. This was also true of nonoperative interventions; however, history of pulmonary embolism, and use of therapeutic anticoagulation were marginally stronger predictors.
In a representative, multinational sample, operative and nonoperative interventions were half as likely among LSG patients compared with LRYGB; however, overall rates still remained low. These findings, in conjunction with new efficacy data demonstrating comparable long-term weight loss between LRYGB and LSG, provide further support for the safety, effectiveness, and cost efficiency of LSG.
腹腔镜 Roux-en-Y 胃旁路术(LRYGB)和腹腔镜袖状胃切除术(LSG)引起的并发症不容忽视,可能需要进行额外的侵入性干预或再次手术。
本研究旨在确定 LSG 和 LRYGB 术后非手术和手术干预的早期并发症、发生这些并发症的时间范围,以及影响其发生的因素。
来自北美的多机构数据库。
本研究数据来自 2015 年和 2016 年代谢和减重认证和质量改进计划参与者的使用文件。使用 STATA 15 进行统计分析。使用 Χ 进行分类数据的单变量分析,使用独立 t 检验进行连续数据的单变量分析,以确定组间差异。使用多变量逻辑回归分析确定手术和非手术再干预的预测因素。
2015 年和 2016 年,有 243747 例患者接受了 LRYGB 或 LSG,其中 3013 例(1.24%)需要进行第二次手术,1536 例(0.63%)需要进行侵入性但非手术干预。LRYGB 患者的并发症发生率为 5.48%,LSG 患者为 2.28%,最常见的并发症是出血。LSG 患者的非手术和手术干预明显少于 LRYGB 患者(分别为 0.85%和 2.2%)(分别为 0.67%和 2.5%)。肾功能不全,包括透析依赖,是肥胖症患者再次手术的重要预测因素。对于非手术干预也是如此;然而,肺栓塞病史和使用治疗性抗凝剂是更强的预测因素。
在具有代表性的多国样本中,LSG 患者的手术和非手术干预可能性比 LRYGB 患者低一半;然而,总体发生率仍然很低。这些发现,结合新的疗效数据证明 LRYGB 和 LSG 之间长期减重效果相当,进一步支持了 LSG 的安全性、有效性和成本效益。