Oancea C N, Cîmpean A, Ion R, Neamţu J, Biţă A, Scorei I R, Neamţu A S, Rogoveanu O C, Zaharie S I, Birkenmeier G
PhD Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.
Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, Romania.
Curr Health Sci J. 2018 Apr-Jun;44(2):113-117. doi: 10.12865/CHSJ.44.02.03. Epub 2018 Mar 27.
In recent years, the role of zinc in biological systems has been a subject of intense research. Zinc is required for multiple metabolic processes as a structural, regulatory, or catalytic ion. The objective of this study, was to assess the toxicity profile of a newly synthesized zinc-boron molecule on cultured cells. Zinc fructoborate, at different levels of concentration, was tested for its impact on the Vero kidney cell line (ATCC® CCL-81™) using the MTT assay. The compound exhibited a low cytotoxic effect on the cell line. Thus, our study demonstrates that the zinc fructoborate could become a promising dietary supplement molecule.
近年来，锌在生物系统中的作用一直是深入研究的课题。锌作为一种结构、调节或催化离子，是多种代谢过程所必需的。本研究的目的是评估一种新合成的锌硼分子对培养细胞的毒性特征。使用MTT法检测了不同浓度水平的果糖硼酸锌对Vero肾细胞系（ATCC® CCL-81™）的影响。该化合物对细胞系表现出低细胞毒性作用。因此，我们的研究表明，果糖硼酸锌可能成为一种有前景的膳食补充剂分子。
