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通过行为经济学和实施科学转变心理健康服务:三个探索性项目的方案

Transforming Mental Health Delivery Through Behavioral Economics and Implementation Science: Protocol for Three Exploratory Projects.

作者信息

Beidas Rinad S, Volpp Kevin G, Buttenheim Alison N, Marcus Steven C, Olfson Mark, Pellecchia Melanie, Stewart Rebecca E, Williams Nathaniel J, Becker-Haimes Emily M, Candon Molly, Cidav Zuleyha, Fishman Jessica, Lieberman Adina, Zentgraf Kelly, Mandell David

机构信息

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

Department of Medical Ethics and Health Policy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

出版信息

JMIR Res Protoc. 2019 Feb 12;8(2):e12121. doi: 10.2196/12121.

Abstract

BACKGROUND

Efficacious psychiatric treatments are not consistently deployed in community practice, and clinical outcomes are attenuated compared with those achieved in clinical trials. A major focus for mental health services research is to develop effective and cost-effective strategies that increase the use of evidence-based assessment, prevention, and treatment approaches in community settings.

OBJECTIVE

The goal of this program of research is to apply insights from behavioral economics and participatory design to advance the science and practice of implementing evidence-based practice (EBP) for individuals with psychiatric disorders across the life span.

METHODS

Project 1 (Assisting Depressed Adults in Primary care Treatment [ADAPT]) is patient-focused and leverages decision-making heuristics to compare ways to incentivize adherence to antidepressant medications in the first 6 weeks of treatment among adults newly diagnosed with depression. Project 2 (App for Strengthening Services In Specialized Therapeutic Support [ASSISTS]) is provider-focused and utilizes normative pressure and social status to increase data collection among community mental health workers treating children with autism. Project 3 (Motivating Outpatient Therapists to Implement: Valuing a Team Effort [MOTIVATE]) explores how participatory design can be used to design organizational-level implementation strategies to increase clinician use of EBPs. The projects are supported by a Methods Core that provides expertise in implementation science, behavioral economics, participatory design, measurement, and associated statistical approaches.

RESULTS

Enrollment for project ADAPT started in 2018; results are expected in 2020. Enrollment for project ASSISTS will begin in 2019; results are expected in 2021. Enrollment for project MOTIVATE started in 2018; results are expected in 2019. Data collection had begun for ADAPT and MOTIVATE when this protocol was submitted.

CONCLUSIONS

This research will advance the science of implementation through efforts to improve implementation strategy design, measurement, and statistical methods. First, we will test and refine approaches to collaboratively design implementation strategies with stakeholders (eg, discrete choice experiments and innovation tournaments). Second, we will refine the measurement of mechanisms related to heuristics used in decision making. Third, we will develop new ways to test mechanisms in multilevel implementation trials. This trifecta, coupled with findings from our 3 exploratory projects, will lead to improvements in our knowledge of what causes successful implementation, what variables moderate and mediate the effects of those causal factors, and how best to leverage this knowledge to increase the quality of care for people with psychiatric disorders.

TRIAL REGISTRATION

ClinicalTrials.gov NCT03441399; https://www.clinicaltrials.gov/ct2/show/NCT03441399 (Archived by WebCite at http://www.webcitation.org/74dRbonBD).

INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/12121.

摘要

背景

有效的精神科治疗方法在社区实践中并未得到持续应用,与临床试验相比,临床疗效有所减弱。心理健康服务研究的一个主要重点是制定有效且具有成本效益的策略,以增加社区环境中基于证据的评估、预防和治疗方法的使用。

目的

本研究项目的目标是应用行为经济学和参与式设计的见解,推进为全生命周期精神疾病患者实施循证实践(EBP)的科学与实践。

方法

项目1(协助初级保健治疗中的成年抑郁症患者[ADAPT])以患者为中心,利用决策启发法比较在新诊断为抑郁症的成年人治疗的前6周激励其坚持服用抗抑郁药物的方法。项目2(强化特殊治疗支持服务应用程序[ASSISTS])以提供者为中心,利用规范压力和社会地位增加治疗自闭症儿童的社区心理健康工作者的数据收集。项目3(激励门诊治疗师实施:重视团队努力[MOTIVATE])探索如何利用参与式设计来设计组织层面的实施策略,以增加临床医生对循证实践的使用。这些项目由一个方法核心提供支持,该核心在实施科学、行为经济学、参与式设计、测量及相关统计方法方面提供专业知识。

结果

ADAPT项目于2018年开始招募;预计2020年得出结果。ASSISTS项目将于2019年开始招募;预计2021年得出结果。MOTIVATE项目于2018年开始招募;预计2019年得出结果。在提交本方案时,ADAPT和MOTIVATE项目的数据收集已经开始。

结论

本研究将通过改进实施策略设计、测量和统计方法来推进实施科学。首先,我们将测试和完善与利益相关者合作设计实施策略的方法(例如离散选择实验和创新竞赛)。其次,我们将完善与决策中使用的启发法相关机制的测量。第三,我们将开发在多层次实施试验中测试机制的新方法。这三者结合我们3个探索性项目的结果,将使我们在以下方面的知识得到改进:成功实施的原因、哪些变量调节和介导这些因果因素的影响,以及如何最好地利用这些知识来提高精神疾病患者的护理质量。

试验注册

ClinicalTrials.gov NCT03441399;https://www.clinicaltrials.gov/ct2/show/NCT03441399(由WebCite存档于http://www.webcitation.org/74dRbonBD)。

国际注册报告识别号(IRRID):DERR1-10.2196/12121。

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