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[红细胞膜上形成的糖酵解酶复合物(糖酵解代谢体)的假设结构]

[Hypothetical structure of the glycolytic enzyme complex (glycolytic metabolon) formed on erythrocyte membranes].

作者信息

Kurganov B I, Liubarev A E

出版信息

Mol Biol (Mosk). 1988 Nov-Dec;22(6):1605-13.

PMID:3075264
Abstract

A hypothetical structure of the glycolytic enzyme complex (glycolytic metabolon) adsorbed on the inner surface of the erythrocyte membrane has been proposed. Oligomers of integral membrane protein, band 3 protein (anion-transport system), are the anchor site for the complex. The complex is supposed to have a three-fold symmetry axis, perpendicular to the membrane plane, and contains a triple set of the glycolytic enzymes. The complex is in equilibrium with free enzymes; the equilibrium state depends on the physiological state of the erythrocyte.

摘要

有人提出了一种吸附在红细胞膜内表面的糖酵解酶复合物(糖酵解代谢体)的假设结构。整合膜蛋白带3蛋白(阴离子转运系统)的寡聚体是该复合物的锚定位点。该复合物被认为具有一条垂直于膜平面的三重对称轴,并包含三组糖酵解酶。该复合物与游离酶处于平衡状态;平衡状态取决于红细胞的生理状态。

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