Division of Cardiothoracic Surgery, Washington University, St. Louis, Missouri.
Division of Pulmonary and Critical Care Medicine, Washington University, St. Louis, Missouri.
Am J Transplant. 2019 Aug;19(8):2164-2167. doi: 10.1111/ajt.15307. Epub 2019 Mar 18.
Organ allocation for transplantation aims to balance the principles of justice and medical utility to optimally utilize a scarce resource. To address practical considerations, the United States is divided into 58 donor service areas (DSA), each constituting the first unit of allocation. In November 2017, in response to a lawsuit in New York, an emergency action change to lung allocation policy replaced the DSA level of allocation for donor lungs with a 250 nautical mile circle around the donor hospital. Similar policy changes are being implemented for other organs including heart and liver. Findings from a recent US Department of Health and Human Services report, supplemented with data from our institution, suggest that the emergency policy has not resulted in a change in the type of patients undergoing lung transplantation (LT) or early postoperative outcomes. However, there has been a significant decline in local LT, where donor and recipient are in the same DSA. With procurement teams having to travel greater distances, organ ischemic time has increased and median organ cost has more than doubled. We propose potential solutions for consideration at this critical juncture in the field of transplantation. Policymakers should choose equitable and sustainable access for this lifesaving discipline.
器官分配用于移植,旨在平衡公正原则和医学效用,以优化利用稀缺资源。为了解决实际问题,美国分为 58 个供体服务区(DSA),每个服务区构成分配的第一个单元。2017 年 11 月,针对纽约的一起诉讼,一项紧急行动改变了肺分配政策,用捐赠医院周围 250 海里的圆圈取代了 DSA 水平的供体肺分配。包括心脏和肝脏在内的其他器官也在实施类似的政策变化。美国卫生与公众服务部最近的一份报告的调查结果,加上我们机构的数据,表明紧急政策并没有改变接受肺移植(LT)的患者类型或术后早期结果。然而,当地的 LT 数量显著下降,供体和受体在同一 DSA 中。由于采购团队必须前往更远的地方,器官缺血时间增加,器官中位数成本增加了一倍多。我们提出了一些潜在的解决方案,供在移植领域的这个关键时刻考虑。政策制定者应为这一拯救生命的学科选择公平和可持续的准入。