Dimzas D, Diakou A, Koutras C, Gómez Morales M A, Psalla D, Keryttopoulos P, Deligianni D, Kontotasios K, Pozio Edoardo
Laboratory of Parasitology and Parasitic Diseases, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Department of Internal Medicine, General Hospital of Veria, Veria, Greece.
J Helminthol. 2019 Feb 13;94:e33. doi: 10.1017/S0022149X19000075.
Trichinellosis is a cosmopolitan zoonotic parasitic disease caused by the nematodes of the genus Trichinella, through the consumption of raw or semi-raw infected meat from swine, horses and wild animals. This disease has been sporadically reported in Greece since 1946. The aim of the present study was to describe a trichinellosis case in a patient hospitalized in northern Greece, in 2017. A 47-year-old male was admitted to hospital with intense generalized myalgia, periorbital swelling, fever, exhaustion and anorexia. Biochemical and haematological profile showed eosinophilia and elevated creatine phosphokinase (CPK). Anti-Trichinella spp. IgG and IgM antibodies were detected by serology and Trichinella spp. larvae were found in two muscle biopsies by compressorium and histological examination. A larva collected from the muscle biopsy was identified as Trichinella britovi by polymerase chain reaction (PCR). Albendazole (400 mg twice per day × 10 days) was administered and the clinical condition of the patient promptly improved. This is the first identification of T. britovi in a patient in Greece.
旋毛虫病是一种世界性的人畜共患寄生虫病，由旋毛虫属线虫引起，通过食用来自猪、马和野生动物的生的或半熟的受感染肉类传播。自1946年以来，希腊曾零星报道过这种疾病。本研究的目的是描述2017年在希腊北部住院的一名患者的旋毛虫病病例。一名47岁男性因严重的全身性肌痛、眶周肿胀、发热、乏力和厌食入院。生化和血液学检查显示嗜酸性粒细胞增多以及肌酸磷酸激酶（CPK）升高。通过血清学检测到抗旋毛虫属IgG和IgM抗体，并且通过压片法和组织学检查在两份肌肉活检样本中发现了旋毛虫属幼虫。通过聚合酶链反应（PCR）将从肌肉活检样本中采集的一条幼虫鉴定为布氏旋毛虫。给予阿苯达唑（400毫克，每日两次，共10天）治疗，患者的临床状况迅速改善。这是希腊首次在患者中鉴定出布氏旋毛虫。
