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识别自闭症:3 岁前后儿童自闭症谱系障碍“预警”特征的父母报告的潜在转变分析。

Recognising autism: a latent transition analysis of parental reports of child autistic spectrum disorder 'red flag' traits before and after age 3.

机构信息

School of Psychology, Ulster University, Derry, BT48 7JL, Northern Ireland, UK.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2019 Jun;54(6):703-713. doi: 10.1007/s00127-019-01664-3. Epub 2019 Feb 13.

Abstract

PURPOSE

It has been proposed that parents should be educated about child autistic spectrum disorder (ASD) 'red flag' traits to help professionals identify and address concerning behaviours as early as possible. This study aimed to empirically demonstrate that established/recognised 'red flag' traits in the first 3 years of life would reliably predict ASD risk severity in later childhood, associated with established ASD risk correlates and mirroring functioning diagnostic categories.

METHODS

Using retrospective parental report data from the Mental Health of Children and Young People in Great Britain survey (N = 7977), latent class analysis (LCA) and a quasi -latent transition analysis were used to (1) identify profiles of variation in parent reports of child 'red flag' traits before and after age 3 and (2) model transitions in risk from 3 years and below to ≥ 3 years, respectively, per the 'optimal outcome' model.

RESULTS

Three distinct classes, each characterised by variation in parent 'red flag' trait reporting were identified for the '≤ 3 years of age' and the '≥ 3 years of age' data. Both LCA class profiles comprised groups of children characterised by low, medium and high ASD risk. Dose-response effects for a number of recognised ASD correlates across the low, moderate and high risk '≥ 3 years of age' classes seemed to validate older classes in terms of ASD relevance. Over 54% of children characterised by the highest levels of ASD 'red flag' trait probability at 3 years and below (2% of sample), also populated the high-risk class evidenced in the '≥ 3 years of age' LCA.

CONCLUSIONS

Retrospective parental reports of child ASD 'red flag' traits ≤ 3 years of age were reliable indicators of ASD risk in later childhood.

摘要

目的

有人提出,应该对父母进行有关儿童自闭症谱系障碍(ASD)“红色标志”特征的教育,以帮助专业人员尽早识别和处理令人担忧的行为。本研究旨在从实证上证明,生命的头 3 年中已确立/公认的“红色标志”特征将可靠地预测儿童后期的 ASD 风险严重程度,与已确立的 ASD 风险相关因素相关,并反映出功能诊断类别。

方法

使用英国儿童和青少年心理健康调查(MHCYB;N = 7977)中的回顾性父母报告数据,使用潜在类别分析(LCA)和准潜在转移分析,分别(1)识别 3 岁前和 3 岁后儿童“红色标志”特征的父母报告变化的模式,以及(2)根据“最佳结果”模型,分别为 3 岁及以下和≥3 岁时的风险转移建模。

结果

为“≤3 岁”和“≥3 岁”的数据分别确定了三个不同的类别,每个类别都以父母“红色标志”特征报告的变化为特征。LCA 类别的两个轮廓都包含了具有不同 ASD 风险的儿童群体。在“≥3 岁”的低、中、高风险类别中,许多公认的 ASD 相关因素的剂量反应效应似乎都验证了 ASD 相关性的旧类别。在 3 岁及以下(样本的 2%)具有最高 ASD“红色标志”特征概率的儿童中,超过 54%也出现在“≥3 岁”LCA 中表现出的高风险类别中。

结论

3 岁及以下儿童 ASD“红色标志”特征的回顾性父母报告是儿童后期 ASD 风险的可靠指标。

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