Department of Psychology, University of Connecticut, Storrs, CT.
J Dev Behav Pediatr. 2014 May;35(4):247-56. doi: 10.1097/DBP.0000000000000037.
Autism spectrum disorders (ASDs) were once considered lifelong disorders, but recent findings indicate that some children with ASDs no longer meet diagnostic criteria for any ASD and reach normal cognitive function. These children are considered to have achieved "optimal outcomes" (OO). The present study aimed to retrospectively examine group differences in the intervention history of children and adolescents with OO and those with high-functioning autism (HFA).
The current study examined intervention histories in 25 individuals with OO and 34 individuals with HFA (current age, 8-21 years), who did not differ on age, sex, nonverbal intelligence, or family income. Intervention history was collected through detailed parent questionnaires.
Children in the OO group had earlier parental concern, received earlier referrals to specialists, and had earlier and more intensive intervention than those in the HFA group. Substantially more children with OO than HFA received applied behavior analysis (ABA) therapy, although for children who received ABA, the intensity did not differ between the groups. Children in the HFA group were more likely to have received medication, especially antipsychotics and antidepressants. There were no group differences in the percent of children receiving special diets or supplements.
These data suggest that OO individuals generally receive earlier, more intense interventions, and more ABA, whereas HFA individuals receive more pharmacologic treatments. Although the use of retrospective data is a clear limitation to the current study, the substantial differences in the reported provision of early intervention, and ABA in particular, is highly suggestive and should be replicated in prospective studies.
自闭症谱系障碍(ASD)曾被认为是终身障碍,但最近的研究结果表明,一些 ASD 儿童不再符合任何 ASD 的诊断标准,并达到了正常的认知功能。这些儿童被认为达到了“最佳结果”(OO)。本研究旨在回顾性地检查具有 OO 和高功能自闭症(HFA)的儿童和青少年的干预史的组间差异。
本研究检查了 25 名 OO 儿童和 34 名 HFA 儿童(当前年龄为 8-21 岁)的干预史,这些儿童在年龄、性别、非言语智力和家庭收入方面没有差异。干预史通过详细的家长问卷收集。
OO 组的儿童父母更早地关注,更早地向专家转诊,并且比 HFA 组更早、更密集地进行干预。接受应用行为分析(ABA)治疗的 OO 儿童明显多于 HFA 儿童,尽管接受 ABA 的儿童在组间的强度没有差异。HFA 组的儿童更有可能接受药物治疗,尤其是抗精神病药和抗抑郁药。接受特殊饮食或补充剂的儿童在组间没有差异。
这些数据表明,OO 个体通常接受更早、更密集的干预,并且更多地接受 ABA,而 HFA 个体则接受更多的药物治疗。尽管使用回顾性数据是当前研究的一个明显限制,但在早期干预,特别是 ABA 的提供方面,报告的显著差异具有高度提示性,应该在前瞻性研究中得到复制。