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Olfactory proteotyping: towards the enlightenment of the neurodegeneration.

作者信息

Fernández-Irigoyen Joaquín, Santamaría Enrique

机构信息

Proteored-Institute of Health Carlos III (ISCIII), Clinical Neuroproteomics Unit, Navarrabiomed, Navarra Health Department, Public University of Navarra, Navarra Institute for Health Research (IdiSNA), Pamplona, Spain.

出版信息

Neural Regen Res. 2019 Jun;14(6):979-981. doi: 10.4103/1673-5374.249220.

DOI:10.4103/1673-5374.249220
PMID:30762007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6404500/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adbe/6404500/c0ca03a17f5c/NRR-14-979-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adbe/6404500/a61ec979c2f5/NRR-14-979-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adbe/6404500/c0ca03a17f5c/NRR-14-979-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adbe/6404500/a61ec979c2f5/NRR-14-979-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adbe/6404500/c0ca03a17f5c/NRR-14-979-g002.jpg

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本文引用的文献

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Neurobiol Aging. 2019 Jan;73:123-134. doi: 10.1016/j.neurobiolaging.2018.09.018. Epub 2018 Sep 25.
2
Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs.经鼻腔脑递药：抗阿尔茨海默病药物的临床挑战和审批进展更新。
J Control Release. 2018 Jul 10;281:139-177. doi: 10.1016/j.jconrel.2018.05.011. Epub 2018 May 24.
3
Progressive modulation of the human olfactory bulb transcriptome during Alzheimer´s disease evolution: novel insights into the olfactory signaling across proteinopathies.
路易体痴呆症嗅分子失衡的蛋白质组学特征。
Int J Mol Sci. 2020 Sep 2;21(17):6371. doi: 10.3390/ijms21176371.
4
The human olfactory system in two proteinopathies: Alzheimer's and Parkinson's diseases.人类嗅觉系统在两种蛋白病中的变化：阿尔茨海默病和帕金森病。
Transl Neurodegener. 2020 Jun 3;9(1):22. doi: 10.1186/s40035-020-00200-7.
阿尔茨海默病进展过程中人类嗅球转录组的渐进性调控：对跨蛋白病嗅觉信号传导的新见解
Oncotarget. 2017 May 23;8(41):69663-69679. doi: 10.18632/oncotarget.18193. eCollection 2017 Sep 19.
4
Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer's disease progression.嗅球神经蛋白质组学揭示了阿尔茨海默病进展过程中存活途径的时间性紊乱和抑制素复合物的破坏。
Sci Rep. 2017 Aug 22;7(1):9115. doi: 10.1038/s41598-017-09481-x.
5
Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate?神经退行性疾病中的嗅觉功能障碍：是否存在共同的病理基础？
Lancet Neurol. 2017 Jun;16(6):478-488. doi: 10.1016/S1474-4422(17)30123-0.
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Neurobiol Dis. 2018 Jan;109(Pt B):226-248. doi: 10.1016/j.nbd.2016.12.013. Epub 2016 Dec 20.
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Olfactory bulb involvement in neurodegenerative diseases.嗅球在神经退行性疾病中的作用。
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J Proteomics. 2012 Jul 16;75(13):4005-16. doi: 10.1016/j.jprot.2012.05.011. Epub 2012 May 15.