Dou Peng-Hui, Zhang Dan-Feng, Su Cui-Hong, Zhang Xiao-Li, Wu Ying-Jie
Department of Radiotherapy and Chemotherapy.
Department of Gynecology.
Medicine (Baltimore). 2019 Feb;98(7):e14609. doi: 10.1097/MD.0000000000014609.
This protocol of systematic review aims to investigate the effectiveness of electrical stimulation (ES) on adverse events (AEs) caused by chemotherapy in patients with cervical cancer (CC).
This systematic review of randomized controlled trials will be identified through searchers of PUBMED, PsycINFO, Scopus, Opengrey, Cochrane Central Register of Controlled Trials, EMBASE, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Allied and Complementary Medicine Database, and Chinese Biomedical Literature Database. All the sources will be searched from the inception to the date of study search ran. Additionally, websites of clinical trials registry and reference lists provided in relevant studies and reviews will also be searched. Two independent reviewers will evaluate the eligibility criteria of all potential literature, extract the data, and determine the risk of bias for each included study. RevMan 5.3 software will be used to pool the data and to conduct a meta-analysis.
This systematic review will assess the effectiveness of ES on AEs caused by chemotherapy in patients with CC.
The findings of this study may summarize the latest evidence for the ES on AEs following chemotherapy for CC.
PROSPERO CRD42019120191.
本系统评价方案旨在研究电刺激（ES）对宫颈癌（CC）患者化疗引起的不良事件（AE）的有效性。
通过检索PUBMED、PsycINFO、Scopus、Opengrey、Cochrane对照试验中央注册库、EMBASE、护理及相关健康文献累积索引、科学引文索引、补充与替代医学数据库以及中国生物医学文献数据库来识别本随机对照试验的系统评价。所有来源将从起始日期检索至研究检索运行日期。此外，还将检索临床试验注册网站以及相关研究和综述中提供的参考文献列表。两名独立的评审员将评估所有潜在文献的纳入标准，提取数据，并确定每项纳入研究的偏倚风险。将使用RevMan 5.3软件汇总数据并进行荟萃分析。
本系统评价将评估ES对CC患者化疗引起的AE的有效性。
本研究结果可能总结ES对CC化疗后AE的最新证据。
PROSPERO注册号：PROSPERO CRD42019120191。
