与关节炎、滑膜炎和肌腱炎相关的皮肤炎症。第 2 部分：类风湿性关节炎、反应性关节炎、赖特综合征、莱姆病、皮肌炎和红斑狼疮。

Skin inflammation associated with arthritis, synovitis and enthesitis. Part 2: rheumatoid arthritis, reactive arthritis, Reiter's syndrome, Lyme borreliosis, dermatomyositis and lupus erythematosus.

机构信息

Department of Dermatology and Venereology, Freiburg University Medical Center, Medical Faculty, Albert Ludwigs University, Freiburg, Germany.

Department of Rheumatology and clinical Immunology, Freiburg University Medical Center, Medical Faculty, Albert Ludwigs University, Freiburg, Germany.

出版信息

J Dtsch Dermatol Ges. 2019 Feb;17(2):167-181. doi: 10.1111/ddg.13761.

DOI:10.1111/ddg.13761

PMID:30762968

Abstract

Syndromes associated with concurrent skin and joint inflammation frequently pose a therapeutic challenge for both dermatologists and rheumatologists. In part 1 of this review, we discussed psoriatic arthritis as well as the autoinflammatory disorders SAPHO syndrome, Still's disease and Behçet's disease. Part 2 will address rheumatoid arthritis, reactive arthritis, Reiter's syndrome and Lyme borreliosis. In addition, we will discuss dermatomyositis and lupus erythematosus, two common autoimmune disorders that frequently present with both cutaneous and joint involvement. For each of the aforementioned disorders, we will highlight aspects of epidemiology, pathogenesis, clinical presentation, diagnosis and treatment.

摘要

伴发皮肤和关节炎症的综合征常常给皮肤科医生和风湿病学家带来治疗上的挑战。在本综述的第 1 部分，我们讨论了银屑病关节炎以及自身炎症性疾病 SAPHO 综合征、斯蒂尔病和贝赫切特病。第 2 部分将讨论类风湿关节炎、反应性关节炎、瑞特综合征和莱姆病。此外，我们还将讨论皮肌炎和红斑狼疮，这两种常见的自身免疫性疾病常同时伴有皮肤和关节受累。对于上述每一种疾病，我们将重点介绍其流行病学、发病机制、临床表现、诊断和治疗方面的内容。