Denisova E I, Korolev A A, Nikitenko E I, Kirpichenkova E V, Fetisov R N, Kozlov V V, Onishchenko G G
I.M. Sechenov First Moscow State Medical University.
Vopr Pitan. 2018;87(6):22-27. doi: 10.24411/0042-8833-2018-10063. Epub 2018 Nov 13.
A number of studies have shown the relationship between the regular consumption of cruciferous vegetables and the risk of malignant tumors in certain localizations, the activation of mechanisms of alimentary adaptation of the organism under conditions of alien loads, by inducing enzymes of the biotransformation system of xenobiotics. The cruciferous vegetables are distinguished by the presence of minor components, such as indole-3-carbinol, formed during the hydrolysis of glucosinolates. The aim of the investigation was a retrospective study of the content of indoles in students' diet with subsequent quantitative analysis in different comparison groups. The study involved 250 students from a medical university aged 21 to 27 years. To assess the actual nutrition, the developed questionnaires were used, which included the most common products in the Moscow region, sources of indole glucosinolates. It was found that 44% of the respondents didn't include cruciferous vegetables in the diet, and of those who consumed sources of indoles (56% of respondents), only about half received them in the recommended amount. It should also be noted that as in men, in women the most commonly used in the diet product as a source of indoles was cabbage, it was included in the diet of 68% of the respondents who used cruciferous vegetables, rarely pekin cabbage was used (16.3%) and broccoli (16.3%). Cauliflower, radishes, Kale and horseradish was included in the diet of 7.8-14.9% of the students. Less often turnip was consumed - only by 2.1% of the students. No significant differences in the consumption of indoles in the student with deficient, normal or overweight was revealed. Also, there was no correlation between excess weight and the consumption of various indoles sources. The obtained results testify to the extremely low level of alimentary intake of indole-3-carbinol.
多项研究表明，经常食用十字花科蔬菜与某些部位恶性肿瘤的风险之间存在关联，在外界负荷条件下，通过诱导异生物转化系统的酶来激活机体营养适应机制。十字花科蔬菜的特点是含有少量成分，如芥子油苷水解过程中形成的吲哚 - 3 - 甲醇。本研究旨在对学生饮食中吲哚含量进行回顾性研究，并在不同比较组中进行后续定量分析。该研究涉及250名年龄在21至27岁之间的医科大学学生。为评估实际饮食情况，使用了所编制的问卷，其中包括莫斯科地区最常见的产品，即吲哚芥子油苷的来源。结果发现，44%的受访者饮食中不包括十字花科蔬菜，而在食用吲哚来源的人群（占受访者的56%）中，只有约一半的人摄入了推荐量。还应指出的是，与男性一样，女性饮食中最常作为吲哚来源的产品是卷心菜，68%食用十字花科蔬菜的受访者饮食中包含卷心菜，很少有人食用大白菜（16.3%）和西兰花（16.3%）。花椰菜、萝卜、羽衣甘蓝和辣根的食用率在7.8%至14.9%的学生之间。食用芜菁的人更少——只有2.1%的学生。在营养不足、正常或超重的学生中，吲哚摄入量没有显著差异。此外，体重超标与各种吲哚来源的摄入量之间也没有相关性。所得结果证明吲哚 - 3 - 甲醇的饮食摄入量极低。
