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社会经济不平等对工人生活方式干预的可及性、依从性和有效性的影响:一项个体参与者数据荟萃分析和特定公平性重新分析的研究方案。

Socioeconomic inequalities in reach, compliance and effectiveness of lifestyle interventions among workers: protocol for an individual participant data meta-analysis and equity-specific reanalysis.

机构信息

Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands.

Department of Work Health Technology, Netherlands Organization for Applied Scrientific Research TNO, Leiden, The Netherlands.

出版信息

BMJ Open. 2019 Feb 13;9(2):e025463. doi: 10.1136/bmjopen-2018-025463.

Abstract

INTRODUCTION

Obesity and unhealthy behaviour are more prevalent among workers with a low compared with a high socioeconomic position (SEP), and thus contribute to socioeconomic health inequalities. The occupational setting is considered an important setting to address unhealthy behaviours due to the possibility to efficiently reach a large group of adults through worksite health promotion. This paper describes the rationale and design for an individual participant data (IPD) meta-analysis and a socioeconomic equity-specific reanalysis aiming to: (1) investigate socioeconomic differences in the effectiveness of interventions aimed at promoting healthy behaviour and preventing obesity, (2) examine socioeconomic differences in reach and compliance and (3) to investigate underlying factors affecting possible socioeconomic differences.

METHODS AND ANALYSIS

A systematic search was conducted in electronic databases including Embase, Medline Ovid, Web of Science, Cochrane Central and Google Scholar as well as in grey literature and trial registries. Two researchers have independently selected a total of 34 relevant studies (from 88 articles). Responsible researchers of these eligible studies were asked to provide their study data and an assessment of the methodological criteria was done. The data of the intervention studies will be pooled for the IPD meta-analysis, whereas the socioeconomic equity-specific reanalysis will focus on each study separately, stratified for SEP. Both methods will be conducted to investigate socioeconomic differences in effectiveness, reach and compliance (research aims 1 and 2). For research aim 3, different factors, such as population characteristics, organisational work environment and intervention characteristics, will be investigated as possible moderators in the associations between SEP and effectiveness, reach and compliance.

ETHICS AND DISSEMINATION

The Medical Ethical Committee of Erasmus MC declared that the Medical Research Involving Human Subjects Act does not apply to the meta-analyses. The findings will be disseminated through peer-reviewed publications and (inter)national conference presentations.

TRIAL REGISTRATION NUMBER

CRD42018099878.

摘要

简介

与社会经济地位较高的工人相比,社会经济地位较低的工人中肥胖和不健康行为更为普遍,这导致了社会经济健康不平等。由于通过工作场所健康促进有可能有效地接触到大量成年人,因此职业环境被认为是解决不健康行为的重要环境。本文描述了一项个体参与者数据(IPD)荟萃分析和一项针对社会经济公平的特定重新分析的基本原理和设计,旨在:(1)研究针对促进健康行为和预防肥胖的干预措施在社会经济方面的有效性差异,(2)研究可达性和依从性的社会经济差异,(3)研究影响可能的社会经济差异的潜在因素。

方法和分析

在电子数据库(包括 Embase、Medline Ovid、Web of Science、Cochrane Central 和 Google Scholar)以及灰色文献和试验登记处进行了系统搜索。两名研究人员独立选择了总共 34 项相关研究(来自 88 篇文章)。这些合格研究的负责人研究人员被要求提供他们的研究数据,并对方法标准进行评估。干预研究的数据将被汇总进行 IPD 荟萃分析,而社会经济公平特定的重新分析将单独针对每个研究进行,按社会经济地位分层。这两种方法都将用于研究有效性、可达性和依从性方面的社会经济差异(研究目标 1 和 2)。对于研究目标 3,将调查人口特征、组织工作环境和干预特征等不同因素,作为社会经济地位与有效性、可达性和依从性之间关联的可能调节因素。

伦理和传播

伊拉斯谟医学中心的医学伦理委员会宣布,涉及人类受试者的医学研究法不适用于荟萃分析。研究结果将通过同行评议的出版物和(国际)会议报告进行传播。

注册号

CRD42018099878。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d111/6398771/8721a27e7c2a/bmjopen-2018-025463f01.jpg

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